Study Guide Questions for Exam #2 Flashcards

1
Q

What are the symptoms of hypothyroidism?

A

1) Inflammation of the thyroid gland
2) Lethargy
3) Apathy
4) Memory impairment
5) Emotional changes
6) Slow speech
7) Deep, coarse voice
8) Edema of the eyelids and face
9) Dry skin
10) Slow pulse
11) Constipation
12) Weight gain
13) Abnormal mesnes

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2
Q

What are the therapeutic effects of liothyronine?

A
  • It is indicated for use as a replacement or supplemental treatment for hypothyroidism of any etiology.

-Myxedema, thyroiditis, goiter, cretinism

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3
Q

What are some nursing interventions for hyperthyroidism?

A

It can be treated with PTU (Polylithouracil) or Methimazaole; PO medication

-Record vital signs
-Monitor PT weight
-LABS, pregnancy test
-Administer iodine preparations for tachycardia as prescribed
-Prepare radioactive iodine therapy

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4
Q

What are some patient educations for Beta Blocker therapy ex. propranolol?

A

By blocking beta receptors, propranolol can control cardiac symptoms that result from hyperthyroidism, such as palpations and tachycardia

  • Do not crush or chew extended release tabs
  • Take the drug at the same time each day in relation to meals
  • Instruct patients that certain food can interfere with absorption of thyroid hormones; soy products [estrogen], cruciferous vegetables [broccoli and cabbage], iodized salt, shellfish [iodine], and coffee
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5
Q

What is the patient education on self-administration of insulin?

A

-Insulin injections should be rotated to prevent lipodystrophy, tissue atrophy, or hypertrophy.

-Doses should not be withheld during illness, including infections and stress

-It should be administered SUBCUT, at 45-90 degree angle; The 90 degree angle is made by raising the skin and fatty tissue, and the insulin is injected into the pocket between the fat and the muscle.

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6
Q

What insulin can be given IV?

A

Regular insulin

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7
Q

What may St.John’s wort alert and affect when taking tolbutamide?

A

It may alter metabolism of repaglinide and affect the blood glucose level when taken with tolbutamide

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8
Q

What are the sulfonylurea (Glipizide) adverse effects ?

A

1) Hypoglycemia
2) Hyponatremia
3) Dyspnea
4) Angioedema
5) Porphyria
6) GI bleeding

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9
Q

What are the rights of admin?

A

1) Right dose
2) Right medication
3) Right patient
4) Right time
5) Right route/form
6) Right documentation

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10
Q

What are the phases of the nursing process?

A

ADPIE or ADOPIE

1) Assessment
2) Diagnosis
3) Planning
4) Implementation
5) Evaluate

(O is for outcome identification, it goes before planning)

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11
Q

What does bioequivalent mean?

A

Equal in the rate and extent to which the active pharmaceutical ingredient becomes available at the site of drug action

** If two products are bioequivalent than for all intents and purposes they are the same **

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12
Q

What does synergistic mean?

A

Describes the effects of two drugs when the effect of the two is greater together than when given alone

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13
Q

What are the routes of med admin?

A

1) Parenteral
-SubCut
-IV, IVP, IVPB
-IM
ID
2) Rectal
3) Vaginal
4) Inhaled
5) Oral (PO)
6) Sublingual/ Bucca
7) Topical

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14
Q

What medications does Gingko interacts with to increase bleeding?

A

Gingko biloba can increased bleeding with anticoagulant/antiplatelet drugs

EX: heparin, warfarin, ticlopidine, dipramidole, clopidogrel, aspirin

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15
Q

What happens to a medication when it is protein-bound, but the patient has a low albumin level?

A

If a specific drug is protein bound and the
patient has low albumin levels there will be
a decrease in binding sites. This will increase the amount of free drug in the blood potentially causing drug accumulation and toxicity

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16
Q

What is the patient education for St.John’s wort?

A

St.John’s wort induces the metabolism of
certain drugs so it may
render them
ineffective if doses are not raised. It can cause
Serotonin Syndrome when combined with
antidepressants, amphetamine, and cocaine.

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17
Q

What is the patient education for Gingko biloba?

A

Gingko biloba can cause increased bleeding and should not be taken with anticoagulant drugs.

  • It can interact with medications that lower
    seizure threshold in PTs taking antihistamines, antidepressants, and antipsychotics
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18
Q

What is the mechanism of action for an adrenergic agonist?

A

They are drugs that stimulate the sympathetic nervous system

1) Dialates pupils
2) Dialates bronchiols
3) Increased HR
4) Constricts blood vessels
5) Relaxes smooth muscles of GI
7) Relaxes bladder muscle
8) Relaxes uterine muscle

19
Q

What is the mechanism of action for an adrenergic agonist?

A

They are drugs that stimulate the sympathetic nervous system

1) Dilates pupils
2) Dilates bronchioles
3) Increased HR
4) Constricts blood vessels
5) Relaxes smooth muscles of GI
7) Relaxes bladder muscle
8) Relaxes uterine muscle

20
Q

What are the effects of atropine?

A

It is an anticholinergic

1) Increases heart rate
2) Relax smooth muscle of GI
3) Relax bladder (urine retention)
4) Decrease salivary secretions
5) Bronchi dilated
6) Dilated pupils

21
Q

What is the action of dopamine?

A

1) Increased cardiac output
2) Increased BP
3) Improved renal blood flow

22
Q

What is the best indication of use of dopamine?

A

Improves BP, cardiac output, urine output in treatment of shock unresponsive to fluid replacement

-Increases renal perfusion

23
Q

What is the action metformin?

A

Increases binding of insulin to receptors, improves tissue sensitivity to insulin, increases glucose transport to skeletal muscles and fatty tissues, decreases glucose production in the liver by reducing gluconeogenesis, and reduces glucose absorption from the intestines.

24
Q

What is the Somogyi effect?

A

A hypoglycemic condition that usually occurs in the predawn hours of 2:00 a.m.-4:00 a.m., where a rapid decrease of blood glucose happens during the nighttime hours stimulates a release in hormones to increase blood glucose by lipolysis, gluconeogenesis, and glycogenolysis

** Management includes monitoring glucose between 2-4am and lowering bedtime insulin dose)

25
Q

What are the adverse effects of sulfonylurea?

A
  • The most common adverse effect is hypoglycemia

1)Hypoglycemia
2)Anaplastic anemia
3) Leukopenia
4)Thrombocytopenia
5)Hyperhidrosis
6)Nausea
7) Vomiting
8) Hepatic failure

26
Q

What is a cholinergic crisis?

A

It includes severe muscle weakness that can lead to respiratory paralysis and arrest. S&S include miosis (irregular pupil constriction)

1)Pallor
2)Sweating
3) Vertigo
4) Vomiting
5) Salivation
6)Nausea
7)Diarrhea
8)Bradycardia
9)Fasciculation (involuntary muscle twitching)

** Usually occurs 30-60 minutes after taking anticholinergic drugs**

  • Due to continuous depolarization of postsynaptic membranes that creates a neuromuscular blockade

Nursing intervention:
-Provides respiratory support via mechanical ventilation and O2
-Administer atropine to reverse
-Have resuscitation equipment available

27
Q

What is the indication of use for desmopressin?

A

1) Treatment of diabetes insipidus
2) For bleeding patients with hemophilia A
3) Sometimes used for management of GI bleeding

  • Vascular & increased water absorption by kidneys
28
Q

What are the adverse actions of Edrophonium chloride (Tensilon) adverse action ?

A

This is a drug to increase muscular strength in myasthenia gravis (short acting for dx purpose)

1) Muscle weakness
2) Dyspnea
3) Abdominal cramping
4) Drooling, tearing, sweating
5) Bradycardia

29
Q

What are the effects of adrenergic drugs?

A

1) Bronchodilators (Bronchospasm) (Beta 2)
2) Uterine muscle relaxant (Beta 2)
3) Nasal decongestant (Alpha 1)

30
Q

What is the drug action for carbidopa-levodopa?

A

Transmission of levodopa to brain cells for conversion to dopamine, carbidopa blocks the conversion of levodopa into dopamine in the intestine and peripheral tissues. Carbidopa is added to the levodopa to inhibit the peripheral restruction of levodopa; thus more levodopa is available for transport to the brain cells for conversion to dopamine

31
Q

What is the indication for carbidopa-levodopa?

A

To treat Parkinson’s disease or parkinsonism.

Treats tremor and rigidity

32
Q

What is the patient education on Alzheimer’s disease pharmacotherapy?

A

1) Explain to the patient and family the purpose for the prescribed drug therapy
2) Clarify times for drug dosing and schedule to the family member responsible for the PT meds
3) Inform family members of available support groups such as the Alzheimer’s association

33
Q

What is pharmacodynamics?

A

Interactions between medications and target cells, body systems, and organs to produce effects. ·

Agonists- binds to or mimics receptor ·

Antagonist- Blocks the usual receptor ·

Partial agonist - can do both 5 receptors

34
Q

What is pharmacokinetics?

A

How medications travel through the body

1) Absorption
2) Distribution
3) Metabolism
4) Excretion

35
Q

What is the drug action of Biguanide?

A

An oral antihyerglycemic agent that limits glucose production and absorption and by increasing the body’s sensitivity to insulin

36
Q

What is the indication for methylphenidate?

A
  • Indication deficit/hyperactivity disorder (ADHD)

-Narcolepsy

37
Q

What are the effects of atropine after admin?

A

1) Increased heart rate
2) Decreased GI and respiratory secretions
3) Reversal of muscarinic effects
4) May have a spasmolytic action on the biliary and genitourinary tracts

Blocks acetylcholine by occupying the muscarinic receptor

38
Q

What is Inotropic?

A

Action that increases myocardial contraction stroke volume

39
Q

What is Chronotropic?

A

An action that decreases heart rate

40
Q

What is Dromotropic?

A

An action that decreases conduction of heart cells

41
Q

What is the action of adrenergic receptors (Alpha 1)?

A

Increases cardiac contractility (vasoconstriction),
dilates pupil, decreases salivary gland secretion, increase bladder and prostere contraction

42
Q

What is the action of adrenergic receptors (Alpha 2)?

A

Inhibits norepinephrine release promotes vasodilation

-Lowers BP
-Decreased GI motility and tone

43
Q

What is the action of adrenergic receptors (Beta 1)?

A

-Increases cardiac contractibility and HR

-Increases renin secretion, and BP

44
Q

What is the action of adrenergic receptors (Beta 2)?

A

-Decreases GI tone and motility bronchodilation
-Increases blood flow in skeletal muscles
-Relaxes smooth muscles of uterus
-Activates liver glycogenesis (increase blood glucose)