Structure Images Flashcards by joelle wasikowski

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penam

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penem

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carbapenem

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cephem

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monobactam

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benzylpenicillin (penicillin G)

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penicllin V, more orally bioavailable due to the oxygen electronegativity

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methicillin (not sensitive to hydrolysis by beta lactamases)

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naficillin (not sensitive to hydrolysis by beta lactamases)

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oxacillin (beta lactamase resistant)

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cloxacillin (beta lactamase resistant)

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dicloxacillin (beta lactamase resistnat)

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ampicillin

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amoxicillin

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pipericillin

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cephazolin (parenteral due to reactive leaving group)
1st gen

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cephalexin (non reactive leaving group)
1st gen

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cefuroxime (parenteral and oral)
2nd gen

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ceftazidime
3rd gen

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cefixime
3rd gen

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cefepime
4th gen
parenteral and stablilized against beta lactamases

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ceftaroline
5th gen
prodrug

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clavulanic acid
beta lactamase inhibitor

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sulbactam
beta lactamase inhibitor

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tazobactam
beta lactamase inhibitor

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avibactam
beta lactamase inhibitor

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cefotitan
parenteral and stable vs beta lactamases

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imipenem
derivative of theinamycin
more reactive than penicillins
inhibits beta lactamases
hydrolyzed by dehydroepeptidase-1
broad spectrum activity

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cilastatin sodium
dehydropeptidase-1 inhibitor
administered with imipenem

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azteonam disodium
monobactam agent
parenteral
resistant to beta lactamases

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vancomycin

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teicoplanin

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oritavancin

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telavancin

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dalbavancin

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quinupristin

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dalfopristin

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linezolid

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tedizolid

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2-deoxystrepamine
(in aminoglycoside structures)

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streptidine
(part of aminoglycosides)

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tobramycin

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plazomycin

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Amikacin A

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gentamycin

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neomycin B

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streptomycin

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erythromycin A

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clarithromycin
6OH turned to methyl

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azithromycin
C9 becomes methylene amino

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clindamycin

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tetracycline

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minocycline
(no C6 hydroxyl)

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doxycycline
(no C6 hydroxyl)

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demeclocycline

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tigecycline

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sarenocycline

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chloramphenicol

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quinolone

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cinnolone

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1,8 naphthyridone

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pyridopyrimidone

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ciprofloxacin
2nd gen

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levofloxacin
3rd gen

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moxifloxacin
fourth gen

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ozenoxacin
new quinolone