Structure and function 2 Flashcards
what is the dermo epidermal junction
connecting point between oueter most layer and whats underneath
where are Melanocytes situated
lower most part of epidermis - baso layer
function of dermo epidermal junction
functions exchange of nutrients between dermis and epidermis
helps skin resist mechanical force etc
supporting anchor point for outer skin
regulates what goes in and out - cells
is the dermo epidermal junction permeable or semi permeable
semi permeable
what are hemidesmosomes
proteins that anchor epithelial cells to the basement membrane
what is bullous pemphigoid
autoimmune skin disorder that causes large fluid filled blisters
immune system mistakenly attacks proteins in the skin that help bind the epidermis to dermis
what is epidermolysis bullosa
iherited disorder with blister formation due to mechanical trauma
cells in dermis
mainly fibroblasts , macrophages, mast cells, lymphocytes, langerhas cells
fibres in dermis
collagen , elastin
what ethnicicy has a thciker dermis
asian, hispanic, latino, African/ american skin types
what ethnicity has larger and more numerous fibroblasts
african/ american
what are ifbroblasts
cell found in connective tissue
play a role in woud healing and maintaining strucral integrity of tissues
key function of fibroblasts
synthesize and secrete colagen and other proteins
wound jealing
whom are collagen fibres thicker in
africanx
hereditary angioma
mutation causing too many blood vessels so causes purpley rashes
chronic lymphoedema
serum haletered and congested in legs
may be consequence of infection
what is neurofibromatosis
genetic condition causing tumours along the nervous system
what makes collagen
fibroblasts
overproduction of collagen
keeloid
