Stroke Flashcards
What are the clinical features of stroke?
- sudden onset
- focal neurological deficit
- symptoms lasting more than 24 hrs
*symptoms for less than 24hrs is a TIA transcient ischaemic attack
What are the 2 types of stroke diagnosis?
- Cerebral Infarction
- Cerebral Haemorrhage
What is the pathophysiology of acute ischaemic stroke?
1) reduction of cerebral blood flow
2) Ischaemia causes alterations in cellular chemistry
3) Cellular necrosis
How much glucose does the bran use per day?
125 g / day
What are the causes of ischaemic stroke?
1) thrombosis
2) Emboli (from heart or from nearby arteries)
What is the most common mechanism of ischaemic stroke?
Large vessel atherosclerosis
What are some treatments for secondary stroke prevention?
-Aspirin (anti-coagulant)
What are is the impact of re-canalization on ischaemic stroke outcome?
Early recanalisation is strongly associated with improved functional outcome and reduced mortality
What is a TIA (transcient Ichaemic Attack)?
TIA is neurological deficit lasting less than 24hours attributable to cerebral or retinal ischaemia
how long do most TIAs last?
60 mins
What are the causes of TIAs?
Causes of TIAs and the same as stroke.
1) Atherosclerosis (large arteries)
2) small cerebral vessel disease.
3) cardiac emboli
What conditions does TIA / stroke mimic?
- siezures
- syncope
- hypoglycaemia
- migraine
- confusion
What are the characteristics of an anterior circulation TIA / stroke ?
- Dysphasia (inability to generate speech)
- Apraxia (inability to perform planned action)
- Inattention
- amarausis fugax (monocular or binocular vision loss)
What are the characteristics of a posterior cirulation TIA / stroke?
- Ataxia (the loss of full control of bodily movements)
- Diplopia (double vision)
- Vertigo (feel like they are swaying)
- Bilateral Symptoms
What circulatory problems are associated with :
- visual fields disturbances
- Hemiparesis (weakness of one side of body)
- Hemisensory loss
- Dysarthria (difficult articulation of speech)
Either circulation
internal carotid or vertebral