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Block 10 > Streptococci > Flashcards

Streptococci Flashcards

1
Q

facultative anerobes

A

streptococci

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2
Q

alpha-hemolytic strep

A

S. pneumococci, and viridans

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3
Q

beta-hemolytic strep

A

S. pyogenes, S. agalactiae

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4
Q

gamma-hemolytic strep

A

S. salivarius

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5
Q

Group A strep

A

S. pyogenes

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6
Q

Group B strep

A

S. agalactiae

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7
Q

Streps that are untypable by the Lancefield system

A

S. pneumoniae and viridans

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8
Q

strep are catalase _____

A

negative

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9
Q

staph are catalase _____

A

positive

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10
Q

strep are oxidase _____

A

negative

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11
Q

Neisseria are oxidase

A

positive

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12
Q

GAS diseases

A 
Pharyngitis
Scarlet fever (uncommon)
Puerperal sepsis (uncommon)
Erysipelas
Septicemia
Tonsilits
Cellulitis
Impetigo
Necrotizing fasciitis
Toxic shock syndrome
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13
Q

Sequelae of GAS

A 
acute rheumatic fever (ARF)
acute glomerulonephritis (AGN)
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14
Q

Sequela of GAS pharyngitis

A

ARF

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15
Q

Rheumatic heart disease epidemiology

A

low-income, developing countries

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16
Q

Sequela of GAS skin infections

A

acute glomerulonephritis

17
Q

ARF and AGN are _____-mediated diseases

A

immune

18
Q

Oxygen stable GAS hemolysin

A

streptolysin S (SLS)

19
Q

Oxygen sensitive GAS hemolysin

A

streptolysin O (SLO)

20
Q

GAS virulence factors

A 
SLS/SLO
hyaluronic acid capsule
M protein
lipteichoic acid (LTA)
Streptococcal pyrogenic exotoxin A (SpeA), SpeB, etc.
21
Q

Hyaluronic acid capsule VF mechanism

A

S. pyogenes hyaluronic acid is identical to huma hyaluronic acid. Antiphagocytic. No antibodies against it.

22
Q

Stain that allows you to see hyaluronic acid capsule

A

india ink

23
Q

Sortase-anchored surface protein. C-terminal half is conserved. N-terminus useful for serotyping. Major antophagocytic factor. Adhesin.

A

M protein

24
Q

Adhesin. PAMP that causes innate immune cells to secrete cytokines and chemokines (not as powerful as LPS from gram negative bacteria)

A

Lipoteichoic acid (LTA)

25
Q

GAS superantigens that massively activate the immune system and can create cytokine storms, leading to sepsis and death

A

Streptococcal pyrogenic exotoxin A (SpeA), SpeB, etc.

Block 10 (16 decks)

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