Antihypertensives

Question 1

function of kinins (including bradykinin)

Answer 1

act locally on blood vessels to cause vasodilation

Question 2

catecholamines are made from

Answer 2

tyrosine

Question 3

name 3 catecholamines

Answer 3

epinephrine
norepinephrine
dopamine

Question 4

Inhibits uptake of norepinephrine into vesicles, decreasing sympathetic tone which reduces TPR, CO, renin release, and BP.

Answer 4

Reserpine

Question 5

Side effect: increases suicidal tendencies

Answer 5

Reserpine

Question 6

Ends with -azosin

Answer 6

Alpha-1 blockers

Question 7

Alpha-1 blocker mainly used as an antihypertensive.

Answer 7

Prazosin

Question 8

Alpha-1 blockers that are used for the treatment of symptoms of benign prostatic hyperplasia.

Answer 8

Terazosin

Doxazosin

Question 9

Side effects of these drugs are first-dose hypotension, dizziness, vertigo, drowsiness, and palpitations.

Answer 9

Alpha-1 blockers

Question 10

Non-selective alpha-adrenergic blockers

Answer 10

phentolamine

penoxybenzamine

Question 11

Use with low renin HTN

Answer 11

dihydropyridine CCB

Question 12

IV use in hypertensive emergency from ECLAMPSIA

Answer 12

Hydralazine

Question 13

Side effects include autoimmune reactions

Answer 13

Hydralazine

Question 14

Administered IV for hypertensive emergencies

Answer 14

Diazoxide
Fenoldopam
Nitroprusside

Question 15

Open K channels

Answer 15

Minoxidil

Diazoxide

Question 16

Inhibits insulin release

Answer 16

Diazoxide

Question 17

D1 agonist

Answer 17

Fenoldopam

Question 18

10 min half-life

Answer 18

Fenoldopam