Stras: CSF Flashcards
- The functions of the CSF include all of the
following except:
A. Removal of metabolic wastes
B. Producing an ultrafiltrate of plasma
C. Supplying nutrients to the CNS
D. Protection of the brain and spinal cord
B. Producing an ultrafiltrate of plasma
- The CSF flows through the:
A. Choroid plexus
B. Pia mater
C. Arachnoid space
D. Dura mater
C. Arachnoid space
- Substances present in the CSF are contolled by the:
A. Arachnoid granulations
B. Blood-brain barrier
C. Presence of one-way valves
D. Blood-CSF barrier
B. Blood-brain barrier
- The CSF tube labeled 3 is sent to:
A. The hematology department
B. The chemistry department
C. The microbiology department
D. The serology department
A. The hematology department
- The CSF tube that should be refrigerated is:
A. Tube 1
B. Tube 2
C. Tube 3
D. Tube 4
C. Tube 3
Even distribution of blood in all tubes
Intracranial hemorrhage
Xanthochromic supernatant
Intracranial hemorrhage
Concentration of blood in tube 1 is greater than in tube 3
Traumatic tap
Specimen contains clots
Traumatic tap
The presence of xanthochromia can be caused by all of the following except:
A. Immature liver function
B. RBC degradation
C. A recent hemorrhage
D. Elevated CSF protein
C. A recent hemorrhage
- A web-like pellicle in a refrigerated CSF specimen is indicative of:
A. Tubercular meningitis
B. Multiple sclerosis
C. Primary CNS malignancy
D. Viral meningitis
A. Tubercular meningitis
- Given the following information, calculate the CSF WBC count: cells counted, 80; dilution, 1:10; large Neubauer squares counted, 10.
A. 8
B. 80
C. 800
D. 8000
C. 800
- A CSF WBC count is diluted with:
A. Distilled water
B. Normal saline
C. Acetic acid
D. Methylene blue
C. Acetic acid
- A total CSF cell count on a clear fluid should be:
A. Reported as normal
B. Not reported
C. Diluted with normal saline
D. Counted undiluted
D. Counted undiluted
- The purpose of adding albumin to CSF before cytocentrifugation is to:
A. Increase the cell yield
B. Decrease the cellular distortion
C. Improve the cellular staining
D. Both A and B
D. Both A and B
- The primary concern when pleocytosis of neutrophils and lymphocytes is found in the CSF is:
A. Meningitis
B. CNS malignancy
C. Multiple sclerosis
D. Hemorrhage
A. Meningitis
- Neutrophils with pyknotic nuclei may be mistaken for:
A. Lymphocytes
B. Nucleated RBCs
C. Malignant cells
D. Spindle-shaped cells
B. Nucleated RBCs
- The presence of which of the following cells is increased when a CNS shunt malfunctions?
A. Neutrophils
B. Macrophages
C. Eosinophils
D. Lymphocytes
C. Eosinophils
- Macrophages appear in the CSF following:
A. Hemorrhage
B. Repeated spinal taps
C. Diagnostic procedures
D. All of the above
D. All of the above
- Nucleated RBCs are seen in the CSF as a result of:
A. Elevated blood RBCs
B. Treatment of anemia
C. Severe hemorrhage
D. Bone marrow contamination
D. Bone marrow contamination
- Following a CNS diagnostic procedure, which of the following might be seen in the CSF?
A. Choroidal cells
B. Ependymal cells
C. Spindle-shaped cells
D. All of the above
D. All of the above
- Hemosiderin granules and hematoidin crystals are seen in:
A. Lymphocytes
B. Macrophages
C. Ependymal cells
D. Neutrophils
B. Macrophages
- Myeloblasts are seen in the CSF:
A. In bacterial infections
B. In conjunction with CNS malignancy
C. Following cerebral hemorrhage
D. As a complication of acute leukemia
D. As a complication of acute leukemia
- Cells resembling large and small lymphocytes with cleaved nuclei represent:
A. Lymphoma cells
B. Choroid cells
C. Melanoma cells
D. Medulloblastoma cells
A. Lymphoma cells
- The normal value of CSF protein is:
A. 6–8 g/dL
B. 15–45 g/dL
C. 6–8 mg/dL
D. 15–45 mg/dL
D. 15–45 mg/dL
- CSF can be differentiated from plasma by the
presence of:
A. Albumin
B. Globulin
C. Prealbumin
D. Tau transferrin
D. Tau transferrin
- In plasma, the second most prevalent protein is IgG; in CSF, the second most prevalent protein is:
A. Transferrin
B. Prealbumin
C. IgA
D. Ceruloplasmin
B. Prealbumin
- Elevated CSF protein values can be caused by all of the following except:
A. Meningitis
B. Multiple sclerosis
C. Fluid leakage
D. CNS malignancy
C. Fluid leakage
- The integrity of the blood-brain barrier is measured using the:
A. CSF/serum albumin index
B. CSF/serum globulin ratio
C. CSF albumin index
D. CSF IgG index
A. CSF/serum albumin index
- Given the following results, calculate the IgG index: CSF IgG, 50 mg/dL; serum IgG, 2 gm/dL; CSF albumin, 70 mg/dL; serum albumin, 5 gm/dL.
A. 0.6
B. 6.0
C. 1.8
D. 2.8
C. 1.8
- The CSF IgG index calculated in Study Question 27 is indicative of:
A. Synthesis of IgG in the CNS
B. Damage to the blood-brain barrier
C. Cerebral hemorrhage
D. Lymphoma infiltration
A. Synthesis of IgG in the CNS
- The finding of oligoclonal bands in the CSF and not in the serum is seen with:
A. Multiple myeloma
B. CNS malignancy
C. Multiple sclerosis
D. Viral infections
C. Multiple sclerosis
- A CSF glucose of 15 mg/dL, WBC count of 5000, 90% neutrophils, and protein of 80 mg/dL is suggestive of:
A. Fungal meningitis
B. Viral meningitis
C. Tubercular meningitis
D. Bacterial meningitis
D. Bacterial meningitis
- A patient with a blood glucose of 120 mg/dL would have a normal CSF glucose of:
A. 20 mg/dL
B. 60 mg/dL
C. 80 mg/dL
D. 120 mg/dL
C. 80 mg/dL
- CSF lactate will be more consistantly decreased in:
A. Bacterial meningitis
B. Viral meningitis
C. Fungal meningitis
D. Tubercular meningitis
B. Viral meningitis
- Measurement of which of the following can bereplaced by CSF glutamine analysis in children with Reye syndrome?
A. Ammonia
B. Lactate
C. Glucose
D. -ketoglutarate
A. Ammonia
- Prior to performing a Gram stain on CSF, the specimen must be:
A. Filtered
B. Warmed to 37C
C. Centrifuged
D. Mixed
C. Centrifuged
- All of the following statements are true about
cryptoccocal meningitis except:
A. An India Ink preparation is positive
B. A starburst pattern is seen on Gram stain
C. The WBC count is over 2000
D. A confirmatory immunology test is available
C. The WBC count is over 2000
- The test of choice to detect neurosyphilis is the:
A. RPR
B. VDRL
C. FTA
D. FTA-ABS
B. VDRL