Stoke and CVA Flashcards
cerebrovascular accident
CVA
old term for stroke, may still be heard in hospitals
penumbra
area around infarct that is not dead yet that clinicians are trying to save w/Tx
causes of ischemic stroke
large a thrombosis
embolism
lacunar
sources of embolic strokes
arterial (carotid, aorta)
heart (atrial, ventricular, valvular)
paradoxical emboli
other causes of ischemic stroke
watershed infarcts hypercoagulable disorders vasculitis vasospasm moyamoya
large artery thrombosis
bascially like a MI of brain
best type of stroke to treat w/tPA
plaques rupture -> platelets -> WBC -> block aa
atrial sources of emboli
A fib/flutter (most common)
atrial septal aneurysm (congenital)
atrial tumors/myoxoma
ventricular sources of emboli
cardiomyopathy
MI (most common)
ventricular aneurysms (most common post MI)
cardiomyopathy
weak and dilated ventricle isn’t pumping efficiently -> blood stasis and thrombus formation
hypertrophic usually forms the clot
MI
part of wall is not moving, creating stasis -> mural thrombosis
valvular cardiac emboli
rheumatic mitral stenosis prosthetic valves infective and non-infective endocarditis nonbacterial thrombotic endocarditis (CA) calcific valves bicuspid aortic valves inflammatory valvulitis
carotid a artherosclerosis/stenosis
may cause embolic or thrombotic strokes
lacunar infarct
-forms in subCx areas of brain supplied by small deep penetrating aa arising from big aa
-BP does not decrease in smaller vessels of brain like it does elsewhere in body, therefore HTN can be devastating to the small vessels of the brain
-may be d/t atheroemboli or lipohyalinosis
frequently asymptomatic
watershed infarcts
when MAP <60
disorders which are more likely to cause arterial clotting
antiphospholipid Ab syndrome
anticardiolipid Abs
lupus anticoagulants
hperhomocysteinemia
other hypercoagulable states
CA prego (increased E) hormone replacement therapy prolonged bedrest/immobility, MI, stroke myeloproliferative disorders (polycythemia vera or essential throbocytosis)