STIs Flashcards
Chlamydia symptomatic?
Mostly asymptomatic
Chlamydia A to C serovars cause
eye infection– trachoma leads to blindness
Chlamydia D to K serovars cause
genital infection– cervicitis, dyspareunia, prostatitis, etc
Chlamydia in women if left untreated can ascend into upper genital tract to cause ____. Which leads to:
PID;
infertility, tubo-ovarian abscess, ectopic pregnancy, chronic pelvic pain
Chlamydia in neonates can acquire C.trachomatis and lead to
neonatal conjunctivitis & pneumonia
Specimens to send for chlamydia
Women:
Men:
Women: vaginal or endocervical swab or 1st catch urine
Men: 1st catch urine, urethral swab, rectal swab
Diagnosis/test of choice for chlamydia
Nucleic acid amplification test (NAAT)
Gonorrhea symptomatic?
Asymptomatic
Gonorrhea presentation in men
- Most infections are acute & symptomatic
- Urethritis
- Epididymitis
- With purulent discharge & dysuria after 2-5 day incubation period (range: 1-14 days)
Gonorrhea presentation in women
- Cervicitis
- Vaginitis
- Often asymptomatic/atypical
- may also lead to PID like chlamydia
- DGI
Gonorrhea presentation in neonates
Neonatal conjunctivitis
- With profuse exudate and swelling of the eyelids
Specimen(s) to send for gonorrhea
- Discharge ‘down below’— ________
- Conjunctivits— ____
- Gonorrhea pharyngitis— ____
- DGI– ____
Depends on presentations
Eg.
- Discharge ‘down below’— high vaginal swab, endocervical swab, urethral swab, urine
- Conjunctivits— eye swab
- Gonorrhea pharyngitis— throat swab
- DGI– blood culture
Diagnosis/test of choice for gonorrhea
Nucleic acid amplification test (NAAT) on urine or swab samples (Adv: rapid test)
Transmission routes for syphilis
Sexual, intimate contact with infectious lesions blood transfusions, transplacental → congenital syphilis
Syphilis: “The Great Imitator” almost any organ can be affected is at which stage?
Secondary stage
Rash, fever, malaise, infectious, lesions occur at which stage of syphilis?
Secondary
Aneurysm formation/aortitis, neruosyphilis can occur at which stage of syphilis?
Tertiary/latent
Common lab test for syphilis
Serology
Herpes simplex virus (HSV) 1: via _____ contact; or can cause genital herpes via _____ contact
via oral-to-oral contact; or can cause genital herpes via oral-to-genital contact
HSV 2 causes
genital herpes
Transmission route of HSV
direct contact
Primary infection of HSV: symptomatic?
Commonly asymptomatic
HSV virus: does it remain latent?
Yes, remains latent and is present for life
HSV can also cause other infections like:
Eye infections (eg. herpetic keratitis)
Serious infections (eg. encephalitis, neonatal infection)
Diagnosis of HSV
PCR (will need swab in UTM or VTM)
Transmission of human papilloma virus (HPV)
direct skin-to-skin contact
HPV causes
cutaneous (skin) or mucocutaneous warts
High risk HPV infection is causally associated with
- cervical cancer
- oropharyngeal cancer
Low risk HPV causes for
genital warts
Diagnosis of HPV
clinical examination, cytology, nucleic acid amplification tests (NAAT)
HSV can reactivate with the trigger of some factors like:
menstruation
tiredness
stress
sunlight