Antibiotic resistance Flashcards

1
Q

What is VRE

A

Vancomycin resistant enterococci

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2
Q

What is CRE

A

carbapenem-resistant Enterobacteriaceae

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3
Q

Germs that are classified under urgent threats (which means require aggressive action)

A

Acinetobacter
Candida Auris
Clostridioides difficile
Enterobacteriaceae (Eg.salmonella, E.coli)

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4
Q

Germs that are classified under concerning threats’: (which means require prevention action)

A

Group A strep

Group B strep

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5
Q

Germs that are classified under serious threats (which means require sustained action)

A
  • Enterobacteriaceae (ESBL-producing)
  • Enterococci (VRE)
  • Pseudomonas aeruginosa
  • Staphylococcus aureus
  • Streptococcus pneumoniae
  • Tuberculosis
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6
Q

Acinetobacter are usually found in _____

A

hospitals

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7
Q

Enterobacteriaceae (ESBL-producing) is a resistance problem esp. in ______

A

coliforms

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8
Q

Pseudomonas aeruginosa is ______ resistant

A

multi-drug

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9
Q

Top 2 most common pathogen of wound infection

A
  1. Staphy aureus

2. Group A strep

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10
Q

Empirical therapy for meningitis:

A

ceftriaxone + vancomycin

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11
Q

Importance of DOT (directly observed therapy)

A

makes sure patients are compliant

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12
Q

Serious side effects of MDR TB infection

A
depression
psychosis
hearing loss
hepatitis
kidney impairment
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13
Q

What is MIC?

A

The minimum concentration which inhibits growth

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14
Q

What does it mean when MIC is low?

A

Pathogen very susceptible to drugs; the drugs are more effective antimicrobial agents

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15
Q

What class of antibiotic is MRSA always resistant to?

A

BETA-LACTAMS

eg. amoxicillin, penicillin

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16
Q

Default treatment of MRSA

A

IV antibiotics eg. vancomycin

17
Q

If patient has a serious infection/sepsis, default antibiotic prescribed is

A

ceftriaxone (beta-lactam)

18
Q

Resistance to ceftriaxone is known as ____

A

ESBL

19
Q

Default antibiotics for ESBL

A

Carbapenems for eg. meropenem, imipenem