STI treatment and investigation Flashcards

1
Q

chlamydia 1st line

A

doxycycline 7 days BD

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2
Q

chlamydia 2nd line

A

azithromycin 1g once then 500mg OD for 2 days

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3
Q

chlamydia in pregnancy

A

azithromycin

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4
Q

is there a TOC for chlamydia

A

no

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5
Q

ix for chlamydia

A

NAAT

  • male - first pass urine
  • female - VVS

if symptomatic male - urethral swab for GS + Microscopy

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6
Q

gonorrhoea 1st line

A

IM ceftriaxone 1g

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7
Q

gonorrhoea needle phobic

A

oral cefixime 400mg + oral azithromycin 2g

both single dose

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8
Q

gonorrhoea ix

A

NAAT

  • male - first pass urine
  • female - VVS

if symptomatic male - urethral swab for GS + Microscopy + NG culture

female - cervical swab - GS + microscopy + NG culture

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9
Q

gonorrhoea and chlamydia ix in throat / rectum

A

throat- pharyngeal swab
rectum - anorectal swab
for NAAT

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10
Q

is there a TOC for gonorrhoea

A

yes

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11
Q

syphilis 1st line

A

benzathine penicillin IM

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12
Q

syphilis 2nd line

A

doxycycline

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13
Q

what is the TOC for syphilis

A

monitor VDLR levels

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14
Q

examples of non-treponemal tests

A

rapid plasma reagin (RPR)

venereal diseases research laboratory (VDRL)

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15
Q

examples of treponemal tests

A

TP-EIA (TP enzyme immunoassay)

TPHA - TP haemagglutination test

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16
Q

treponemal test: positive

non-treponemal test: positive

A

active syphilis infection

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17
Q

treponemal test: negative

non-treponemal test: positive

A

false positive

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18
Q

treponemal test: positive

non-treponemal test: negative

A

successfully treated syphilis

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19
Q

syphilis diagnostic test

A

swab of ulcer for treponema pallidum PCR

venous blood - syphillis IgG/IgM EIA

20
Q

syphilis screening

A

IgM/IgG Elise

21
Q

during latent syphilis how is it dx

A

serology

22
Q

tx herpes gingivostomatitis

A

oral aciclovir

chlorhexidine mouthwash

23
Q

tx herpes cold sores

A

topical aciclovir

24
Q

tx herpes genital sores

A

oral aciclovir

25
Q

ix herpes

A

swab of base of ulcer for NAAT / HSV PCR

venous blood - HSV-type specific serology (only under specialist guidance)

26
Q

ix trichomoniasis

A

High vaginal swab - ideally posterior fornix

wet mount and microscopy

27
Q

trichomoniasis tx

A

oral metronidazole 5-7 days or once off dose 2g

28
Q

tx genital warts - solitary keratinised

A

cryotherapy

29
Q

tx multiple non-keratinised genital wart

A

topical podophyllum

30
Q

2nd line treatment genital warts

A

imiquimod

31
Q

tx crabs

A

malathion lotion

32
Q

ix candidiasis (thrush)

A

not needed if clinical features highly suggestive

if doubt
female: swab of vaginal walls (HVS) for GS + microscopy, candida culture

male: swab of sub-prepuce (penile) for candida culture

+/- anti fungal susceptibility

33
Q

tx candidiasis (thrush)

A

oral fluconazole 150mg single dose

34
Q

tx candidiasis (thrush) 2nd line or pregnant

A

topical cotrimazole pessary

35
Q

what can be added to pessary / oral in tx of candidiasis (thrush) if vulval s/s

A

topical imidazole

36
Q

ix recurrent candidiasis (thrush)

A

HVS, OGTT

37
Q

tx recurrent candidiasis (thrush)

A

oral fluconazole induction 3 days then weekly for 6 months

38
Q

bacterial vaginosis ix

A

microscopy - clue cells - HVS

positive whiff test

39
Q

tx bacterial vaginosis

A

oral metronidazole 400mg BD 5 days

or 2mg once (latter not in breast feeding)

40
Q

tx bacterial vaginosis in pregnancy

A

oral metronidazole or topical clindamycin

41
Q

prostatitis ix

A

MSSU for C + S

42
Q

prostatitis tx

A

ofloxacin 14 days

43
Q

tx epididymo-orchitis

A

ceftriaxone 500mg IM single dose + doxycycline 100mg oral 10-14 days

44
Q

what tests are done for CT and NG as well as NAAT - male

A

if symptomatic - urethral swab for gram stain and microscopy

NG culture

45
Q

what specimen is used for CT and NG in a male for gram stain and microscopy
(and NG culture)

A

uretheral swab if symptomatic

46
Q

what specimen is used for NG gram stain and microscopy and culture in females

A

cervical swab

47
Q

HIV ix

A

venous blood

HIV Ab/Ag test