Stem Cells!

Question 1

Hayflick Limit

Answer 1

40-50 cell divisions is a mx. before cells stop growing and instead start aging

Question 2

Stem cell don’t follow ___?

Answer 2

Hayflick Limit
(Have the ability to renew themselves for long periods of time)

Question 3

Stem Cells

2

Answer 3

1. Unspecialized, undifferentiated cells

2. Can be induced to differentiate into cells with a specialized function

Question 4

Types of stem cells?

Answer 4

1. Embryonic
2. Adult (somatic)
3. Incuded pluripotent

Question 5

Hierarchy (3)

Answer 5

1. Totipotent
2. Pluripotent
3. Multipotent

Question 6

Totipotent

Answer 6

Can give rise to embryo/placenta cells PLUS any cell in the body

Question 7

Pluripotent

Answer 7

Can rise rise to any cell in the body

Question 8

Multipotent ex:

Answer 8

Blood cells, muscle, nerve, bone, other tissues

Question 9

Embryonic Stem Cells
What?
From Where?

Answer 9

Cells from a 5 day pre-implantation stage embryo
Pluripotent - develop into any cell in the body
Come from inner cells of the blastocyst

Question 10

Inner cells of the blastocyst…

Answer 10

Form all the cells in the body!

Question 11

4 types of embyronic stem cells

Answer 11

1. Ectoderm
2. Mesoderm
3. Endoderm
4. Germline

Question 12

Adult Stem Cells

Answer 12

RARE cells located in different tissues that have constant turnover
MULTIpotent - can develop into several cells - not all.
Important for regenerative + repair functions