Enzymes and Metabolic Pathways - 8 Flashcards
1
Q
Acetylation
A
+acetyl to histone
loosens
more gene expression
2
Q
Methylation
A
to histone or DNA
tightens
less gene expression
3
Q
euchromatin
A
looser
more accessible to DNA pol
4
Q
heterochromatin
A
tighter
less accessible
5
Q
Why do histones and DNA stay together
A
Charges - histone + (amino acids
DNA - phosphates
6
Q
nucleosome
A
DNA and protein
7
Q
Catabolic
A
breaks down complex molecules
release energy
Exergonic
8
Q
Anabolic
A
small to big
require energy
Endergonic
9
Q
Transition state
A
Reactants (substrates) contort into unstable configuration
Used to reduce activation energy
tightest bonding, least stable
10
Q
In enzymes - substrates bind to the enzymes ____ and have _____ fit
A
active site
induced fit
11
Q
Enzymes induce transition state by: (3)
A
- Bringing reacting molecules together
- Bringing substrates into close proximity in correct orientation
- Reduces reliance on random collisions
