statins Flashcards
patient 69 yo with clinic signs of ASCVD, should they be started on statin? if so which
high intensity
- atorvastatin 40-80mg
or
- rouvastatin 20- 40mg
how much with high intensity statin lower LDL
Lowers by 50%
Patient does not have clinical symptoms of ASCVD but does have LDL of 192. Should they be placed on statin is so which one
high intensity
atorvastatin 40-80mg
or
Rouvastatin 20-40mg
Patient 78 yo with clinic signs of ASCVD, should they be started on statin? if so which
Moderate intensity due to age over 75 atorvastatin 10-20mg rosuvastatin 5-10mg simvastatin 20-40mg lovastating 40mg pravastatin 40-80mg fluvastatin 80mg pitavastatin 2-4mg
how much does moderate therapy reduce LDL levels
reduces by 30 to 50%
Patient 55 yo with diabetes with LDL 150 asks about starting statins what would you tell them?
candidate for moderate dose therapy statin atorvastatin 10-20mg rosuvastatin 5-10mg simvastatin 20-40mg lovastatin 40mg pravastatin 40-80mg fluvastatin 80mg pitavastatin 2-4mg
Patient 55 yo with diabetes with LDL 150 asks about starting statins, they have no clinical signs of ASCVD but when you do the 10y risk assessment you find score of 7.5%. Should they be started on medications which one?
yes, high dose statin
Atorvastatin 40-80mg
Rosuvastating 20-40mg
Patient 60yo with out DM has risk assessment score of 5% should they be started on medicatoins
yes moderate intensity atorvastatin 10-20mg rosuvastatin 5-10mg simvastatin 20-40mg lovastatin 40mg pravastatin 40-80mg fluvastatin 80mg pitavastatin 2-4mg
how often should the 10y risk ASCVD be done
every 4 to 6 years
A patient with no DM less than 40 with LDL 166 is not on statin are there any other areas to consider on initiation of therapy
consider life style,
consider family Hx, CAC score, ABI, hs-CRP >2, LDL greater than 160.
How much LDL decrease can be seen with use of low dose statins
should decrease LDL by 30% simvastatin 10mg lovastatin 20mg pravastatin 10-20mg fluvastatin 20-40mg pitavastatin 1mg
how does bile acid sequestrant effect LDL? Triglycerids?
decrease LDL and increase triglycerides
How does ezetimibe (Zetia) work and whats its affect on LDL
cholesterol absorption inhibitor, decreases LDL
What effect does Niacin have on LDL, HDL, and triglycerides
decrease LDL, increase HDL, decrease triglycerides
