SSTI & DFI Tx Guidelines Flashcards
1
Q
Animal/Human Bites
A
- Augmentin (DOC)
- Alternative: 2nd/3rd Gen Cepha + Anaerobic coverage
- B-Lactam Ax: Cipro/Levo + Anaerobic coverage OR Moxiflox
- established Infxn: 7-14 days
- Preemptive Tx: 3-5 days
2
Q
Impetigo
A
- Few Lesions: Mupirocin topical
- Many Lesions/Outbreak: Dicloxacillin or Cephalexin
- Strep ONLY: PCN
- Allergies/MRSA: Doxy, Clinda, or Bactrim
3
Q
MILD Diabetic Foot Infxn
A
- 1st Line: Dicloxacillin, Cephalexin, Clindamycin
- Recent Antibiotics? Switch to Augmentin, Levo, or Moxiflox
- MRSA RF? switch to Bactrim or Doxycycline
1-2 weeks
4
Q
MODERATE Diabetic Foot Infxn
A
- 1st LIne: Moxiflox, Augmentin, or Cipro/Levo + Clindamycin/Metronidazole
- Pseudomonas RF? switch to Cipro/Levo + Clinda/Metronidazole
- MRSA RF? ADD Vanc, Linezolid, Doxy, or Bactrim
2-3 weeks (cover anaerobes)
5
Q
SEVERE Purulent SSTI
A
- I&D and C&S
- Empiric: Vanc, Dapto, or Linezolid
- Targeted: MRSA (Vanc, Dapto, Linezolid) or MSSA (Nafcillin, Cefazolin, or Clindamycin)
5 days
6
Q
Necrotizing Fasciitis
A
- Emergent Surgical Inspection/Debridement
- Empiric: Vanc AND Zosyn
- Targeted: Strep Pyogenes (PCN AND Clindamycin) Polymicrobial (Vanc AND Zosyn)
Tx until fever has been absent for 48 hours
7
Q
MILD Non-Purulent SSTI
A
PO Penicillin VK, Cephalosporin, Dicloxacillin, or Clindamycin
5 days
8
Q
MILD Purulent SSTI
A
incision & drainage (I&D)
9
Q
SEVERE Non-Purulent SSTI
A
- Empiric Tx: Vanc AND Zosyn
- Swith to narrow Tx after C&S
5 days
10
Q
MODERATE Purulent SSTI
A
- I&D and C&S
- Empiric: Bactrim or Doxycycline
- Targeted: MRSA (Bactrim or Doxycycline) or MSSA (Dicloxacillin or Cephalexin)
5 days
11
Q
MODERATE Non-Purulent SSTI
A
IV Penicillin, Ceftriaxone, Cefazolin, or Clindamycin
5 days
12
Q
SEVERE Diabetic Foot Infxn
A
- 1st Line: Zosyn, Carbapenem, or Cefepime + Clinda/Metronidazole
- MRSA RF? ADD Vanc, Linezolid, or Dapto
2-3 weeks
