Spectrum of Activity

Question 1

Aminoglycosides

Answer 1

G+(gent only) and G- (aerobes only)
- MSSA (gent w/ cell wall agent)
- MRSA (gent w/ cell wall agent)
- Pseudomonas

Question 2

Anti-MRSA Cepha (Ceftaroline)

Answer 2

G+, G-, and anaerobes
- PRSP
- MSSA
- MRSA (only B-Lactam)

Question 3

Ticarcillin

Answer 3

G- Aerobes only
- Pseudomonas

Question 4

TMP-SMX

Answer 4

G+, G- aerobes ONLY (NO ANAEROBIC)
- MSSA
- MRSA (CA-MRSA too)
- Pneumocystis carnii/jirovecii* D.O.C

Question 5

Penicillin G

Answer 5

G+ and G- and Anaerobes (ADA)

Question 6

Tela, Dalba, Oritavancin

Answer 6

G+ ONLY (aerobes and anaerobes)
- PRSP
- VRE (some since similar to vanc)
- MSSA
- MRSA
- VISA
- VRSA (orita only)

Question 7

Polymyxins (Colistin & Polymyxin B)

Answer 7

G- Aerobes ONLY
- Pseudomonas

Question 8

Nafcillin

Answer 8

• G+ aerobes only
• MSSA* D.O.C

Question 9

Zosyn

Answer 9

G+, G-, and anaerobes
- MSSA
- Pseudomonas
- BDA

Question 10

Monobactam (Aztreonam)

Answer 10

G- Aerobes ONLY
- Pseudomonas

Question 11

Daptomycin

Answer 11

G+ ONLY (aerobes and anaerobes)
- PRSP
- VRE* (enteroccus faecium AND faecalis) D.O.C
- MSSA
- MRSA
- VISA/VRSA/LRSA

Question 12

Macrolides

Answer 12

G+, G-, and anaerobes
- +/- MSSA
- Legionella* (A,C are best)

Question 13

Piperacillin

Answer 13

G+ and G- and anaerobes (ADA,BDA)
- Pseudomonas
- BDA

Question 14

Synercid

Answer 14

G+ ONLY (aerobes and anaerobes)
- PRSP
- VRE* (enterococcus FAECIUM ONLY)
- MRSA
- MSSA

Question 15

Cepha/B-lactam-i combos

Answer 15

G+, G-, and anaerobes
- Pseudomonas
- including ESBL and AmpC bac (Ceft/Avi also covers KPC and OXA-48)

Question 16

4th Gen Cepha (Cefepime) and Cefiderocol

Answer 16

G+ (cefepime only), all G-, and anaerobes
- PRSP (cefepime)
- MSSA (cefepime)
- Pseudomonas

Question 17

3rd Gen Cepha

Answer 17

G+, G-, and anaerobes
- PRSP* (Ceftriaxone only) D.O.C
- MSSA (ceftriaxone only)
- Pseudomonas (Ceftazidime only)
- HENPECKSSS

Question 18

Augmentin/Unasyn

Answer 18

G+, G-, and anaerobes
- MSSA
- BDA

Question 19

Levo, Moxi, Delafloxacin

Answer 19

G+, G-, and Atypical
- PRSP
- MSSA
- MRSA (Dela only)
- Pseudomonas (Levo/Dela only, NOT Moxi)
- Legionella*

Question 20

Carbapenems

Answer 20

G+, G-, and anaerobes (Dori and Meropenem are the BEST)
- MSSA
- Pseudomonas (NOT ertapenem)
- BDA

Question 21

Clindamycin

Answer 21

G+ aerobes and G- anaerobes (NO G- Aerobes)
- MSSA
- CA-MRSA*
- BDA (resistance emerging)

Question 22

2nd Gen Cepha

Answer 22

G+, G-, and anaerobes
- MSSA
- BDA (Cefoxitin, cefotetan, and Cefmetazole only)
- HENPEK

Question 23

1st Gen Cepha

Answer 23

G+, G-, and anaerobes
- MSSA*
- PEK

Question 24

Ciprofloxacin

Answer 24

Poor G+, good G- and atypical
- +/- MSSA
- Pseudomonas
- Legionella

Question 25

Vancomycin

Answer 25

G+ ONLY (aerobes and anaerobes)
- PRSP*
- MRSA*
- MSSA
- C. Diff* (PO only)

Question 26

Metronidazole

Answer 26

ANAEROBES ONLY
- BDA (DOT)
-C. Diff

Question 27

Linezolid and Tedizolid

Answer 27

G+ ONLY (aerobes and anaerobes)
- PRSP
- VRE* (enterococcus faecium AND faecalis) D.O.C
- MSSA
- MRSA
- VISA/VRSA

Question 28

Tretacycline, Doxycycline, Minocycline (Tetracyclines)

Answer 28

G+, G-, anaerobes, atypical
- MSSA
- +/- MRSA
- Legionella

Question 29

Ampicillin

Answer 29

G+, G-, and anaerobes

Question 30

Tigecycline, Eravacycline, Omadacycline (Tretracycline Analogs)

Answer 30

G+, G-, and anaerobes
- MSSA
- MRSA
- BDA