SSRIs and St. Johns Wort

Question 1

serotonin syndrome common symptoms?

Answer 1

delirium, agitation, sweating, myoclonus, shivering, coarse tremors, extensor plantar, increased muscle response.

Question 2

severe cases of serotonin syndrome

Answer 2

hyperthermia, seizures, rhabdomyolysis, renal failure, cardiac dysrhythmias, DIC

Question 3

SSRI drug name

Answer 3

fluoxetine, Prozac

Question 4

two facts about SSRIs?

Answer 4

first line for depression and safer than other antidepressants.

Question 5

contraindications for fluoxetine?

Answer 5

MAOIs, St. Johns wort.
TCAs, warfarin, digoxin, diazepam.

Question 6

which drug increases the therapeutic effects of fluoxetine?

Answer 6

TCAs

Question 7

fluoxetine potentiates which drugs?

Answer 7

warfarin, digoxin, diazepam.

Question 8

takes how long for the full effect of SSRIs?

Answer 8

4-6 weeks

Question 9

washout when changing classes of meds takes about how long?

Answer 9

2-5 weeks

Question 10

prozac urges you to monitor which organ function?

Answer 10

liver
(because of the PROtein)

Question 11

what is a major nursing consideration for SSRIs?

Answer 11

suicidal ideation.

Question 12

CNS side effects of fluoxetine?

Answer 12

tremors, anxiety.
headache, drowsiness

Question 13

GI side effects of fluoxetine?

Answer 13

changes in taste, n/v, weight gain.

Question 14

GU side effects of fluoxetine?

Answer 14

sexual dysfunction, cystitis, urinary retention, painful menstruation.

Question 15

why is painful menstruation ironic with fluoxetine?

Answer 15

it is used to treat PMDD

Question 16

St. Johns wort is also called what?

Answer 16

herbal prozac

Question 17

do not take which antidepressant for more than how many weeks together with St. Johns wort?

Answer 17

MAOI, 2 weeks.

Question 18

all the contraindications for St. John’s Wort
everything on the left side of the board except…

Answer 18

benzodiazepines, tyramine foods, TCAs, and anticonvulsants.
(lithium is the exception)

Question 19

anticonvulsants can’t be with which drug/herbal product?

Answer 19

St. John’s wort

Question 20

further St. John’s wort contraindications
war is SAD- so pray to St. John, he’ll take away everything that is hurting you.

Answer 20

warfarin, statins, digoxin, anticoagulants.

Question 21

side effects of St. Johns wort
F, D, C, P, H_N

Answer 21

fatigue, dizziness, confusion, photosensitivity, hypertension,