CNS depressants and Muscle Relaxants

Question 1

CNS depressants reduce what?

Answer 1

nervousness, irritability, excitability.

Question 2

CNS depressants are d____ d______

Answer 2

dose dependent

Question 3

midazolam (versed) is what class of drug and what category?

Answer 3

CNS depressants, and benzodiazepine.

Question 4

midazolam would be used for which indications?

Answer 4

pre-operatively, or for moderate or conscious sedation.

Question 5

midazolam can cause two obvious side effects but one less obvious side effect.

Answer 5

anxiolysis and sedation, with amnesia.

Question 6

routes of midazolam are–
for adults:
for children:

Answer 6

IV, PO liquid

Question 7

Valerian is used for?

Answer 7

relieving anxiety, restlessness, and insomnia.

Question 8

adverse effects of valerian?

Answer 8

depression, irritability, restlessness (can cause what it’s treating)

Question 9

valerian is contraindicated in which condition because it is ___toxic.

Answer 9

liver disease, hepatoxic.

Question 10

Valerian may potentiate these two drugs (or classes)

Answer 10

antihistamines, and other CNS depressants.

Question 11

Kava used to relieve what? (basically the same things as before)
+ 2 new things

Answer 11

anxiety, stress, restlessness, and promotes sleep and is a muscle relaxant.

Question 12

Kava is no longer a CNS depressant and is instead a:

Answer 12

muscle relaxant

Question 13

side effects of Kava

Answer 13

visual disturbances, temporary skin discoloration (only with long-term use)

Question 14

potential interactions of kava

Answer 14

sedating drugs:
benzodiazepines, alcohol, barbiturates, and anti-convulsants.

Question 15

contraindications in kava (hint- one thing is similar to valerian)

Answer 15

depression, Parkinson’s, history of stroke, and hepatotoxic.

Question 16

muscle relaxants should be cautioned for use with which sedating “drugs”

Answer 16

alcohol and other CNS depressants.

Question 17

direct acting muscle relaxants work where?

Answer 17

in the skeletal muscles

Question 18

centrally acting muscle relaxants work where?

Answer 18

in the CNS

Question 19

muscle relaxants and their management of spasticity of severe chronic disorders, such as:

Answer 19

MS, cerebral palsy.

Question 20

treatment for toxicity with muscle relaxants?

Answer 20

no treatment, just conservative supportive measures.

Question 21

If muscle relaxants ARE taken with CNS depressants then three steps should be taken.
1.
2.
3.

Answer 21

1. adequate airway maintained
2. EKG monitoring
3. give fluids to prevent crystalluria.

Question 22

Baclofen (Lioresal) has injectable forms where? for what?

Answer 22

injectable used in implantable pumps.
for chronic spastic muscles

Question 23

Baclofen does what with the pump device to ensure a positive response?

Answer 23

give a test dose.

Question 24

Cyclobenzaprine (Flexeril) is what kind of drug?

Answer 24

centrally acting muscle relaxer.

Question 25

what is the most commonly used muscle relaxer?

Answer 25

cyclobenzaprine

Question 26

which forms does cyclobenzaprine come in?

Answer 26

PO and ER (amrix)

Question 27

what is the ER form of cyclobenzaprine called?

Answer 27

amrix

Question 28

the only side effect of cyclobenzaprine?

Answer 28

marked sedation (maybe)