Spondyloarthropathies

Question 1

What is the gene which predisposes?

Answer 1

HLA B27

Question 2

What conditions are associated with this?

Answer 2

Ankylosing spondylitis, reactive arthritis, Crohn’s disease, Uveitis

Question 3

What are the subgroups?

Answer 3

• Ankylosing spondylitis
• Psoriatic arthritis
• Reactive arthritis
• Enteropathic arthritis

Question 4

What is Enthesitis?

Answer 4

Inflammation at the joint between the tendon and bone

Question 5

What is Dactylitis?

Answer 5

Inflammation of the entire digit, sausage fingers

Question 6

What is the diagnosis criteria for ankylosing spondylitis?

Answer 6

Limited lumbar motion
Lower back pain for more than 3 months
Reduced chest expansion

Question 7

What are the clinical features of psoriatic arthritis?

Answer 7

Sacroiliitis, eye disease, nail involvement, dactylitis, enthesitis

Question 8

What is oligoarthritis?

Answer 8

The most common type of juvenile idiopathic arthritis

Question 9

What are the most common routes for infection which then causes reactive arthritis?

Answer 9

Urogenital, enterogenic

Question 10

What is the triad for Reiter’s syndrome?

Answer 10

Urethritis, arthritis, conjunctivitis

Question 11

Name the mucocutaneous lesions associated with reactive arthritis

Answer 11

Keratodema Blenorrhagica - affecting the soles and palms
Circinate balanitis - affecting the penis glans
Painless oral ulcers
Hyperkeratotic nails

Question 12

What is the treatment of reactive arthritis?

Answer 12

NSAIDs
Steroids 
DMARDs 
Antibiotics for the underlying infection 
Physio 
OT

Question 13

What is the treatment for enteropathic arthritis?

Answer 13

Not NSAIDs - can worsen IBD 
Paracetamol, cocodamol 
Steroids 
DMDs
Anti TNF