Spine DDx Flashcards

1
Q

Spinal Ependymoma vs Spinal Astrocytoma:

A

Ependymoma:

  • Child or adult (“E - Elderly).
  • More central in location.
  • Bone remodelling common.
  • 3 - 4 segments long.
  • Low T1 signal
  • Haemosiderin Cap sign on T2.
  • Surrounding cord oedema.
  • Well defined homogenous enhancement
  • Associated cysts common
  • Syrinx more common
  • Haemorrhage more common
  • cervical > thoracic.

Astrocytoma:

  • Child ( “C containing Child”)
  • more eccentric, with fusiform expansion of cord.
  • Cervical > thoracic.
  • Short segment < 4 segments.
  • Bone remodelling less common
  • Low T1 signal
  • Ill defined heterogenous enhancement
  • Syrinx less common
  • Haemorrhage less common
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2
Q

Adult Sacral Mass:

A
Lytic osseous Mets
Sacral stress Fracture
Occult intra sacral meningocele
Chordoma
Lymphoma
Giant cell tumour
Multiple Myeloma
Chondrosarcoma
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3
Q

Paediatric sacrococcygeal Mass:

A
Sacrococcygeal teratoma
Presacral abscess
Chordoma
Neuroblastic tumour
Plexiform neurofibroma
Lymphoma
Chondrosarcoma
Ewings.
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4
Q

Solitary flattened vertebral body:

A
Osteoporosis
Lytic osseous Mets
Plasmacytoma
MM
Steroids
LCH
Giant cell tumour
Ewing Sarcoma
Leukaemia
Lymphoma
Pyogenic OM
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5
Q

Multiple flattened Vertebral Fractures:

A
Trauma
Osteoporosis
Lytic osseous Mets
MM
Leukaemia
Lymphoma
Sickle cell disease
Osteogenesis Imperfecta
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6
Q

Aggressive bony lesion:

A
Lytic osseous Mets
Blastic osseous mets
lymphoma
MM
Pyogenic Infection
Granulomatous OM
LCH
Haemodialysis Spondyloarthropathy
Neurogenic arthropathy
Ewings in child
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7
Q

Diffuse Vertebral body T1 Hypointense Signal

A
Hyperplastic Marrow
Blastic osseous Mets
MM
Lymphoma
Leukaemia
HIV
Sickle Cell
Renal Osteodystrophy
Myelofibrosis
Osteopetrosis
Fibrous dysplasia
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8
Q

Ventral / lateral paraspinal Mass:

A
Lymphadenopathy
 - Lymphoma
 - Mets
Vertebral body Met
Aortic Aneurysm
Paraspinal abscess
Retroperitoneal haemorrhage
Lateral meningocele
Neurogenic tumour:
 - schwannoma
 - Neuroblastoma
 - ganglmioneuroma
Extramedullary haematopoiesis.
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9
Q

Extra dural lesion with solid enhancement

A
Peridural fibrosis
Osseous Mets
Neurofibroma
Schwannoma
Lymphoma
Plasmacytoma
Ewings
LCH
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10
Q

Intra dural intra medullary lesion with solid enhancement:

A

Tumour like conditions:

  • Spinal cord ependymoma
  • Spinal cord astrocytoma
  • Haemangioblastoma
  • Mets: assess bones, and leptomenigneal enhancement.

Demyelinating:

  • MS
  • ADEM
  • Neuromyelitis optica

Cavernous malformation.

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11
Q

Intra dural extra medullary lesion with solid enhancement:

A
schwannoma
Meningioma
Neurofibroma
Myxopapillary ependymoma.
CSF Mets.
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12
Q

INtra dural extra medullary lesion with ring / peripheral enhancement:

A
Arachnoid cyst
Schwannoma cystic
Meningioma cystic
Neurenteric cyst
Meningitis
Cysticercosis
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13
Q

Intra dural extra medullary lesion T1 hyperintense

A
Metal artifact
Filum terminale fibrolipoma
Lipoma
Subdural haematoma
SAH
Lipomyelomeningocele
Dermoid / epidermoid.
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14
Q

Intra dural extra medullary lesion T2 hyperintense T1 isointense:

A
Schwannoma
Neurofibroma
Epidermoid
CSF Mets
Myxofibrillary ependymoma
Cysticercosis.
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15
Q

Vertebral body scalloping:

A
POSTERIOR: "SALMON"
S: spinal cord tumour: astrocytoma, ependymoma, schwannoma.
A: Achondroplasia, acromegaly.
L: Loeys Dietz
M: Marfans, Mucopolysaccharidoses 
O: Osteogenesis Imperfecta
N: NF1 --> lateral menigocele.
ANTERIOR:
Retroperitoneal lymphadenopathy: 
 - Leukaemia
 - Lymphoma
 - TB.
Abdominal aortic aneursym
Down syndrome.
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16
Q

Vertebral Body Focal T1 hyperintense signal

A
Normal
Haemangioma
Degenerative endplate
Focal fatty marrow
Enhancement
Paget
Mets - Melanoma
17
Q

Diffuse Vertebral Body Sclerosis:

A
Discogenic Sclerosis
Sclerotic Mets
Chronic OM
Renal Osteodystrophy
Paget 
Sickle Cell
Osteopetrosis
Radiation
Myelofibrosis
18
Q

Focal Vertebral body Sclerosis:

A
Bone Island
Haemangioma
Degenerative Endplate changes
Sclerotic Mets
Insufficiency fracture
Compression fracture
Chronic OM
ankylosing spondylitis
Osteoid Osteoma.
Ewings in child
19
Q

Enlarged vertebral body with soap bubble appearance:

A
Lytic Mets: lung, thyroid, renal.
MM / plasmacytoma
Osteoblastoma
Giant Cell Tumour
Aneurysmal Bone Cyst
Chordoma
20
Q

Intramedullary Mass:

A
MS
Neuromyelitis Optica
ADEM
Acute transverse myelitis
Ependymoma
astrocytoma
Contusion
Haemangioblastoma
AV malformation
Infarction.
21
Q

Multiple Intra medullary lesions:

A
MS
Mets
ADEM
Haemangioblastoma
Ependymoma (NF2)
22
Q

Intramedullary Lesion no enhancement:

A
Syringomyelia
MS
Contusion
Acute transverse myelitis
astrocytoma
ADEM
23
Q

Intramedullary lesion with diffuse / ill defined enhancement:

A
MS
Acute transverse myelitis
ADEM
Viral myelitis
neuromyelitis optica
Dural AVF
Met
24
Q

Intramedullary lesion with ring / peripheral enhancement:

A
MS
Astrocytoma
Ependymoma
Met
Cysticercosis
25
Q

Intramedullary lesion T2 hyperintense T1 isointense:

A
MS
Neuromyelitis Optica
Acute transverse myelitis
Contusion
Cellular ependymoma
Astrocytoma
Dural AVF
Haemangioblastoma
ADEM
26
Q

Intramural Extramedullary Leptomeningeal enhancement:

A
Gullian barre syndrome
CSF Mets
Meningitis
Myxopapillary ependymoma
Neurofibroma
Schwannoma
27
Q

Marrow summary signal:

A

T1 money sequence

  • Yellow marrow bright
  • Red marrow is darker / isointense to muscle

Red marrow should never be darker than normal disc or muscle on T1.

Red marrow increases if need for haematopoesis.

28
Q

Posterior elements lesion:

A
G: giant cell tumour 
O: osteoblastoma
T: tuberculosis
A: aneurysmal bone cyst
P: Paget disease
E: eosinophilic granuloma