GU DDx Flashcards

1
Q

Adrenal Mass:

A

Adrenal Adenoma

  • Circumscribed small (<2cm)oval homogenous low density mass
  • < 10HU highly specific.
  • Signal drop out on out of phase -> lipid rich.
  • Lipid poor: absolute washout > 60%, relative washout > 40%.

Metastases (lung breast kidney melanoma)

Haemorrhage

Pheochromocytoma

  • Well circumscribed 3-5cm mass
  • MEN IIA or MEN IIB
  • Neurofibromatosis
  • VHL
  • Carney syndrome
  • Tuberous sclerosis
  • Hyperintense T2, heterogenous bright C+

Adrenal myeloipoma

  • T1 hyperintense
  • Focal areas fat suppression

Adrenal TB

  • Chronic: Addisons disease
  • Small Ca++ glands

Adrenal carcinoma:

  • non functional large lesions.
  • May have necrosis, haemorrhage, Ca++

Adrenal collision tumour

Adrenal hyperplasia:
- Normal shape with increased thickness, or nodular.

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2
Q

Hypoechoic adrenal mass:

A
Adenoma
Metastases
Pheochromocytoma
Adrenal haemorrhage
Adrenal cortical carcinoma
Adrenal pyogenic infection (unilateral)
Granulomatous infection (bilateral)
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3
Q

Cystic adrenal Mass:

A
Simple cyst
Abscess
Organising haematoma
Mimics: renal cyst, liver cyst, pancreatic cyst, splenic artery pseudoaneursym.
Cystic adenoma
Cystic neuroblastoma
Cystic pheochromocytoma
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4
Q

Hyper echoic adrenal mass:

A
Adrenal haemorrhage
Calcification:
 - Previous haemorrhage
 - Previous infection
 - Calcified neoplasm (neuroblastoma, myelolipoma, pheochromocytoma)
 - Wolman disease
Myelolipoma
Neuroblastoma
Adrenal cortical carcinoma
Pheochromocytoma.
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5
Q

Bilateral adrenal enlargement:

A
Adenoma
Mets
Haemorrhage / infarction
Adrenal hyperplasia
Pheochromocytoma
Infection: TB, Histoplasmosis, granulomatous disease.
Lymphoma
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6
Q

Medullary nephrocalcinosis:

A
"HAM HOP"
H: hyperparathyroidism
A: (renal tubular) acidosis
M: medullary sponge kidney
H: hypercalcaemia/hypercalciuria
O: oxalosis
P: papillary necrosis

Hyper PTH
- Clusters round Ca++ renal pyramids

Renal tubular acidosis (distal type)

Medullary sponge kidney

  • Tiny calculi disapear with contrast
  • Delayed CECT show renal pyramid blush
  • unilateral less dense medullary nephrocalcinosis.
  • Assocations: ehlers danlos, Carolis, Beckwith Weidemann.

Hyper calcaemia

Oxalosis:

  • Dense Ca++ cortex +/- medulla.
  • Normal sized kidneys
  • Skeletal hyperdensity.

Papillary necrosis

Chronic Pyelonephritis:

  • Punctate or focal Ca++ in cortex and medulla.
  • Cortical thinning over dilated calyces.
  • Kidneys small in size and function.

TB:
- Focal or diffuse amophous Ca++.

Child - frusemide treatment.

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7
Q

Cortical nephrocalcinosis: “COAG”

A

C: cortical necrosis
O: oxalosis
A: Alport syndrome
G: (chronic) glomerulonephritis

Acute cortical necrosis
Hyperoxaluria
Alport syndrome
ARPCKD
Transplant rejection
Chronic GN
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8
Q

Echogenic kidneys:

A

Medical renal disease

  • Diabetic nephropathy
  • Glomerulosclerosis
  • Actube tubular necrosis.
  • HIV nephropathy: enlarged echogenic
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9
Q

Echogenic renal Mass:

A

Angiomyolipoma: shadowing echogenic mass specific.
Atypical malignant renal neoplasm.
Renal calculus
Intra renal gas
Milk of Calcium
Sloughed papillae due to papillary necrosis.

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10
Q

Renal Sinus Lesion DDX:

A

Sinus lipomastosis

Renal Sinus Cyst:

  • Peripelvis: multiple confluent non communicating, surround and compress calyces.
  • Parapelvic: solitary, spherical.

Renal Pelvis clot / haematoma

Vascular lesions:

  • Aneurysm
  • AVM
  • Varices

TCC

Lymphoma

RCC

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11
Q

Gas around Kidney DDX:

A
Emphysematous pyelonephritis
Renal abscess
Emphysematous pyelitis
Renal infarction
Instrumentation
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12
Q

Radiolucent filling defect renal pelvis DDX:

A
Urolithiasis
Blood clot
Fungus ball
TCC:
 - irregular filling defects, amputates calyces.
Renal Papillary necrosis:
 - Sloughed papilla with cavitation of calyx.
 - CLub shaped calyces
 - Analgesic abuse.
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13
Q

Gas within Baldder DDX:

A

Iatrogenic
Bladder fistula
Cystits
Emphysematous cystitis

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14
Q

Filling defect in urinary bladder DDX:

A

Bladder carcinoma:

  • mass protruding into lumen, enhances
  • Cant completely exclude on imaging alone

Bladder calculi

Ureterocele:
- Orthoptopic, cobra head

Blood Clot

BPH
- J shaped ureters

Bladder fistula

Extra vesical pelvic mass.

Fungus ball: Candida.

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15
Q

Cystic Retroperitoneal Mass:

A
Retroperitoneal seroma
Retroperitoneal Sarcoma: 
 - mixoid liposarcoma can have water density
Retroperitoneal lymphocele
Urinoma
Retroperitoneal Abscess
Lymphangioma
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16
Q

Fat Containing Retroperitoneal Mass:

A

Liposarcoma:

  • Large fat and soft tissue components
  • Compresses and displaces retro-peritoneal organs.
  • Invasion uncommmon
  • Liposarcoma is less vascular than AML

Renal AML:

  • Benign hamartoma of blood vessels, muscle, fat.
  • AML will replace part of kidney / claw sign.

Adrenal myelolipoma:
- Fat and soft tissue components +/- Ca++

Teratomas: Met

AIDS: liodystrophy:
- Proliferation of retroperitoneal and mesenteric fat in response to AIDs medication.

Retroperitoneal lipoma:
- Less heterogenous than lipsarcoma.

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17
Q

Hyperechoic Renal Mass DDX:

A

Angiomyolipoma:

  • Well defined hyperechoic mass that is equal to renal sinus
  • May have posterior shadowing
  • Small lesions echogenicity > RCC
  • Large lesion: prominent vascularity
  • May have central necrosis
  • Requires CT.

RCC:

  • 30% hyperechoic
  • Necrosis or anechoic rim favours RCC
  • Large RCC may have Ca++
  • Mass with Ca++ and fat in adult = RCC

Wilms tumour:
- CHild

Fat in renal scar

Milk of Ca++ cyst:
- COmet tail artifact

Renal Calculi:

Renal Papillary Necrosis:
- Echogenic ring in medulla = Necrotic Papilla, surounded by rim of fluid.

Abscess with Gas.

Renal Mets

Renal TB:

  • Papillary destruction with echogenic masses near calyces
  • Ca++ granuloma or dense dystrophic Ca++ with shrunken kidney.

Renal oncocytoma

Renal Trauma.

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18
Q

Infiltrative Renal Lesion DDX:

A

Replaces renal parenchyma without distorting shape. Lacks sharp border of demarcation.

Pyelonephritis:
- Enlarged kidney, striated / wedge foci of reduced C+

TCC

Mets / lymphoma
- Multiple poorly defined renal masses

RCC:
- usually expansile, rarely diffusley infiltrative.

Renal medullary carcinoma:
- Young patient with sickle cell

HIV nephropathy

Renal TB.

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19
Q

Peri renal and subcapsular mass DDX:

A
Haemorrhage:
 - trauma, coagulopathic, tumour (AML / RCC), vasculitis.
Renal Mets / lymphoma
Abscess
Xanthogranulomatous pyelonephritis
urinoma
Retroperitoneal fibrosis
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20
Q

Bilteral Renal Cysts:

A

ADPCKD:

  • Progressively enlarged kidneys, loose function
  • Cysts in liver, pancreas, seminal vesicles.

Acquired cystic disease uraemia:
- Dialysis -> increases risk of RCC.

VHL:
- cysts and tumours of kidney adrenal, pancreas, brain, spinal cord (haemangioblastomas)

Tuberous sclerosis:
- hamartomas brain, lung, heart, skin, kidneys

Medullary cystic Disease:

  • Small kidneys with cysts in medulla, thinned cortex.
  • Progressive renal faliure and anaemia in young patient.
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21
Q

Calcified small lesion in Kidney DDX:

A
Urolithiasis
Renal artery Ca++
Nephrocalcinosis
Medullary sponge kidney
AIDS / opportunistic infections
Renal papillary necrosis - clubbed calyces
Chronic GN / pyelonephritis:
 - Small scared kidneys with small foci Ca++
RCC:
 - foci Ca++ approx 10%
Renal Tb.
22
Q

Renal Nuke Agent summary:

A

Tc-DMSA: renal structure:
- Assess for scarring and infection.

Tc- DTPA: “like CTPA hence we check eGFR”
- filtered thus givens GFR assessment.

Tc-MAG 3: “need your mag wheels to get through tight spots, like renal artery stenosis.

  • Secreted
  • Estimates effective renal plasma flow.
  • ACE study, sick kidney will have marked tracer retention,

ACE study using DTPA, as is a GFR tracer, a sick kidney will have decreased uptake and flow, due to loss of perfusion pressure, hence worsening uptake post ACE.

23
Q

Adrenal Absolute washout:

A

% washout = (Enhanced attenuation - delayed attenuation) / (enhanced attenuation - unenhanced attenuation)

> 60% absolute washout is diagnostic of adenoma.

24
Q

Adrenal Relative Washout:

A

% relative washout = (enhanced attenuation - delayed attenuation) / enhanced attenuation

> 40% relative washout diagnostic adenoma.

25
Q

Pheochromocytoma: 10% lesion

A

10% extra adrenal
10% bilateral
10% malignant
10% familial or syndromic

26
Q

Pheochromocytoma associations:

A
MEN 2A and MEN 2B (usually bilateral intra adrenal)
VHL
NF1
TS
Sturge weber
Carney's triad:
 - Gastric leiomyosarcoma
 - Pulmonary chondroma
 - extra adrenal pheochromocytoma.
27
Q

adrenal Ca++:

A

Wegner granulomatosis
TB
Histoplasmosis
Old haemorrhage

28
Q

Unilateral enlarged Kidney DDx;

A

Pyelonephritis
Acute ureteral obstruction
Renal vein thrombosis
Compensatory hypertrophy

29
Q

Striated nephrogram:

A
Pyelonephritis
Renal Infarct
Renal vein thrombosis or vasculitis
Renal contusion
Acute urinary obstruction
Renal tumour - lymphoma
Radiation nephritis
30
Q

Causes of renal papillary necrosis:

POST CARD:

A

P: Pyleonephritis
O: Obstruction
S: Sickle Cell Disease
T: TB

C: Cirrhosis
A: Analgesics
R: Renal Vein thrombosis
D: DM

31
Q

Unilateral delayed nephrogram DDx:

A

Acute ureteral obstruction
Renal vein thrombosis
Renal artery stenosis
Pyelonephritis

32
Q

Bilateral delayed nephrogram DDx:

A

Bilateral obstruction
Contrast nephropathy
Systemic hypotension
Myeloma Kidney.

33
Q

Ureteral filling defect DDx:

A
Ureteral malignancy (TCC)
Ureteral calculus
Blood clot
Malacoplakia (multiple flat defects)
Leukoplakia
Infectious debris
Sloughed papilla
Benign ureteral mass - fibroepithelial polyp
34
Q

T2 Dark Renal Cyst DDx:

A
Lipid poor AML - think TS
Haemorrhagic Cyst (T1 bright)
Papillary Subtype RCC
35
Q

Renal Artery Doppler RI Values:

A

Normal 0.5 - 0.7
Abnormal > 0.7

Causes for elevated values:
 - Medical renal disease
Ureteric obstruction
 - Hypotension
 - Perinephric collection / haematoma
 - Abdominal compartment syndrome.

Causes for elevated transplant values:

  • ATN
  • Rejection
  • Renal vein thrombosis
  • Drug toxicity
  • Ureteric obstruction
  • perinephric fluid collection.

Abnormally low value: down stream of renal artery stenosis

36
Q

Renal artery doppler with reversed diastolic flow:

A

Renal vein thrombosis
“Reverse M sign”

Common within 1st week post transplant.

37
Q

Post renal transplant renal artery stenosis:

A

within 1st year, most common vascular complication.
“Refractory HTN”

PSV > 200-300 cm/s
PSV ratio > 2.0
Tardus parvis wave form distal to level of stenosis.
Anastomotic jetting.

38
Q

Lateral deviation of ureters:

A

Retroperitoneal adenopathy
Aortic aneursym
Psoas hypertrophy causes proximal urertic lateral deviation.

39
Q

Medial deviation of Ureters:

A
Retroperitoneal fibrosis
Retrocaval ureter - right
Pelvic lipomatosis
Psoas hypertrophy causes medial deviation of distal ureters.
AP resection
40
Q

Solid renal mass:

A
RCC
Oncocytoma
Angiomyolipoma
TCC
Lymphoma
41
Q

Multiple bilateral renal lesions / masses:

A
Lymphoma
Renal infection
RCC
AMLs
Mets
42
Q

Cystic renal mass:

A
Complex cyst
Cystic neoplasm: RCC and Wilms.
Multilocular cystic nephroma: 
 - MJ lesion --> young boys middle aged women.
Abscess
43
Q

Perinephric fluid collection:

A

Perinephric Haemorrhage
Urine leak / extravasation
Pyelonephritis / perinephric infection.

44
Q

Pear shaped bladder (AXR IVP):

A
Pelvic haematoma
Lymphadenopathy
Pelvic lipomatosis
Psoas muscle hypertrophy
Iliac artery aneursym
45
Q

Bladder Wall Ca++:

A
TCC
Schistosomiasis
Cystitis
TB
Urachal carcinoma
46
Q

Dilated Ureter:

A

Ureteral Obstruction
Reflux
Primary megaureter
Prune Belly syndrome.

47
Q

Urethral Stricture:

A
Urethral trauma
Post infectious / inflammatory stricture:
 - gonococcal
 - Chlamydia
Urethral carcinoma
48
Q

Renal artery acceleration time > 0.07

A

> 50% stenosis renal artery

49
Q

Acceleration index < 3m/s

A

> 50% stenosis

50
Q

Renal Resistive index:

A

Normally below 0.7

>0.7 implies something wrong with that kidney.