GI DDx Flashcards
Hypo-attenuating Liver
Fatty liver / hepatic steatosis
Hepatic amyloid
Hyper-attenuating Liver
Absolute attenuation > 75HU on non-con.
Iron overload.
- primary haemochromatosis: liver and pancreas
- secondary haemochromotosis: Liver and spleen.
Medications - amiodarone, gold, methotrexate.
- check lung bases for ILD.
Wilsons disease (Copper)
Glycogen excess.
Thoratrast
Multiple tiny hypo-attenuating hepatic lesions:
Candidiasis: immunocompromised. Mets. Lymphoma Biliary hamartomas. Caroli Disease. Sarcoidosis - check spleen for same.
Hypervascular hepatic Mets:
Neuroendocrine tumours: pancreatic neuroendocrine and carcinoid. RCC Thyroid carcinoma Melanoma Sarcoma
Hepatic Capsular retraction:
Metastatic tumor (commonly post Tx) Fibrolamellar HCC HCC (rare) Epitheloid haemangioendothelioma Intrahepatic cholangiocarcinoma Confluent hepatic fibrosis
Pancreatic Mass without ductal dilation:
Autoimmune pancreatitis Groove pancreatitis Cystic pancreatic tumour Neuroendocrine tumour GIST Peri-pancreatic lymph node Pancreatic Mets: RCC, thyroid, melanoma. Lymphoma
Cystic Pancreatic Neoplasm:
Serous cystadenoma: Senile Grandmother, hypervascular, no duct dilation or tail atrophy, central stellate Ca++. (seen in VHL)
Mucinous cystic neoplasm: mother, benign with malignant potential, single / few large cysts, commonly body / tail, capsule.
Solid Papillary Epithelial Neoplasm (SPEN): daughter, low malignant potential, heterogenous solid cystic mass, haemorrhage, capsule.
Intraductal Papillary Mucinous Neoplasm (IPMN): grandfather, variable - can be malignant, main duct or side branch.
Pancreatic neuroEndocrine neoplasm: commonly central necrosis and Ca++, hypervascular. Hypervascular liver mass with associated pancreatic mass most likely metastatic pancreatic endocrine neoplasm. (Seen in VHL)
Hepatic lesion with a scar:
Focal nodular hyperplasia Fibrolamellar HCC: wild looking, T2 hypointense scar. Cholangiocarcinoma Haemangioma HCC
Liver lesion with a capsule:
Adenoma
HCC
Cystadenoma / cystadenocarcinoma.
Liver lesion with central calcification:
Metastases (especially in colorectal tumors - mucinous)
Fibrolamellar carcinoma (FLC) - wild and large
Cholangiocarcinomas
Hemangiomas
Liver lesion containing fat:
Adenoma HCC Metastatic liposarcoma Angiomyolipoma Glissons capsule lipoma / pseudo lipoma
Consider Dropped gall stone.
Liver lesion containing blood / haemorrhage
Adenoma
HCC
Cystic liver lesion:
Simple cyst Traumatic cyst Bilioma Caroli's disease Cystic Mets Abscesses Hydatid disease Biliary cystadenoma
Hypervascular liver lesion:
Benign:
Focal nodular hyperplasia
Adenoma
Haemangioma (looks like fire on PV, peripheral discontinuous nodular enhancement)
Aggressive:
HCC
Hypervascular Mets: RCC, thyroid, melanoma, neuroendocrine, breast, sarcomas.
Common causes liver capsule retraction:
Cholangiocarcinoma
Mets - commonly treated breast.
Focal atrophy due to biliary or venous obstruction.
Stomach Rams Horn Deformity:
Scarring from peptic ulcer disease.
Granulomatous disease: Crohns, sarcoid, TB, Syphillis.
Scirrhous Carcinoma.
Dilated oesophagus:
Achalasia
Pseudoachalsia
Scleroderma.
Liver mass with capsule retraction
Focal confluent fibrosis Peripheral cholangiocarcinoma Mets / lymphoma. HCC Epithelioid haemangioendothelioma
Fat containing liver mass
Steatosis (normal traversing vessels) Pericaval fat deposition HCC (small foci) Hepatic adenoma Hepatic Mets Hepatic angiomyolipoma (TS, renal AMLs) Alcohol ablated liver tumour Teratoma Liposarcoma
Mosaic / patchy hepatogram:
Passive hepatic congestion Hepatitis Cirrhosis Steatosis Budd Chiari syndrome Hereditary Haemorrhagic Telangiectasia Congenital Hepatic Fibrosis Hepatic sarcoidosis
Hepatic Ca++:
Calcified granuloma (histoplasmosis > Tb)
Hepatic Mets (mucinous colon, breast, ovary, stomach)
Arterial Ca++
Ethiodol treated lesions
Cavernous Haemangioma
Hydatid cyst
Fibrolamellar HCC
Dysmorphic Liver with abnormal Bile Ducts:
PSC Cholangiocarcinoma Cholangitis AIDS cholangiopathy Fibropolycystic liver disease (Caroli disease)
T1 hyperintense Liver lesions:
Steatosis Hepatic adenoma HCC Haemorrhagic hepatic cyst Dysplastic and regenerative nodules Liver haematoma Hepatic Mets Pyogenic abscess Focal nodular hyperplasia Hepatic angiomyolipoma Peliosis
Liver lesion with capsule / Halo:
Hepatic Mets Pyogenic abscess HCC Haematoma Adenoma Hydatid cyst Amebic abscess Focal nodular hyperplasia
Focal Hyperdense Hepatic Mass on Non enhanced CT
Cirrhotic Regenerating Nodule Mass within fatty liver Focal sparing in fatty liver Mets Haematoma Haemorrhage within adenoma / HCC
Focal hepatic echogenic lesion +/- acoustic shadowing:
Focal steatosis Calcified granuloma Haemangioma Mets Pneumobilia Intra hepatic biliary calculi Pyogenic hepatic abscess Portal venous gas HCC Fibrolamellar HCC Cholangiocarcinoma
Pancreatic duct dilation
Chronic pancreatitis
Pancreatic ductal adenocarcinoma
Periampullary tumour
Obstructing distal common bile duct stone
Intra ductal papillary mucinous neoplasm.
Hypovascular Pancreatic Mass:
Pancreatic ductal adenocarcinoma Chronic pancreatitis Mucinous cystic neoplasm Serous cystadenoma Ampullary carcinoma.
Hypervascular Pancreatic Mass:
Pancreatic neuroendocrine tumour Pancreatic Met (RCC) Pancreatic serous cystedoma with multiple enhancing septations.
Cystic Pancreatic Mass:
Intraductal papillary Mucinous Neoplasm (elderly men)
Pancreatic psuedo cyst
Pancreatic serous cystadenoma (“senile head of family”)
Mucinous cystic neoplasm (Mother, body/tail)
Solid Psuedopapillary Neoplasm (Daughter, Race minor)
Atrophy or Fatty replacement pancreas:
Chronic pancreatitis Senescent change Obesity Cystic Fibrosis Cushing syndrome / steroid use Lipomatous pseudohypertrophy Shwachman-Diamond syndrome Agenesis dorsal pancreas.
Infiltration of peripancreatic fat planes:
Acute pancreatits Pancreatic ductal carcinoma Anascara and portal HTN Traumatic pancreatitis Duodenal / gastric ulcer Shock pancreatits Sclerosising mesenteritis Autoimmune pancreatitis Lymphoma
Pancreatic calcifications:
*Pancreatic adenocarcinoma alsomost never shows Ca++.
Chronic pancreatitis
Senescent change
Peripancreatic vascular calcification - splenic artery
Choledocholithiasis
Pancreatic neuroendocrine tumour
Pancreatic serous cystadenoma - central Ca++
Pancreatic muscinous cystic neoplasm - septation Ca++
Solid pseudopapillary Neoplasm - Ca++ common.
Pseudocyst
Distended Gall bladder:
Cholecystits Obstruction of CBD: choledocholithiasis, pancreatic ductal carcinoma, ampullarf carcinoma. Acute pancreatitis. Hepatitis. Gall bladder empyema AIDs Cholangiopathy
Pneumobilia / Pneumo-gall bladder:
Sphincterotomy Choledocholithiasis Patulous Sphincter of Oddi Biliary Enteric Anastomosis Emphysematous cholecystitis. Gass within gall stones. Gall stone ileus / cholecysto-enteric fistula Pyogenic cholangitis.
*Portal venous gas mimic: gas flows toward and collects in periphery of liver, on US causes spiky appearance on portal vein doppler. Biliary gas collects near porta hepatis.
Hyper dense bile within Gall bladder:
Vicarious excretion Layering of small gall stones. Gall bladder sludge. Hepatic / biliary trauma. Milk of calcium bile.
Asymmetric Dilation of Intrahepatic Bile Ducts:
PSC Cholangiocarcinoma ascending cholangitis HCC Hepatic mets or lymphoma AIDs cholangiopathy Recurrent pyogenic cholangitis. Gall bladder carcinoma, with infiltration.
IgG4 disease causes a more diffuse picture of biliary involvement.
Hypointense Lesions in biliary tree on MRCP:
Choledocholithiasis
Pneumobilia
Surgical clip
Post transplantation biliary stricture.
Hypervascular Liver Mets:
Islet cell tumour Carcinoid Thyroid Renal Pheochromocytoma
Liver mass with scar:
FNH: scar T2 bright, delayed enhancement.
Haemangioma
Fibrolamellar HCC: scar T2 dark, delayed partial C+, large wild looking.
HCC
Peripheral cholangiocarcinoma
Focal liver lesion with haemorrhage:
Trauma Hepatic adenoma HCC Hepatic cyst AD polycystic disease
Cystic hepatic Mass:
Hepatic cyst AD polycystic disease Pyogenic abscess Amebic abscess Biliary hamartoma Bilioma Mets.
Focal Hypervascular Liver lesion:
Haemangioma FNH arterial portal shunt THAD HCC Hepatic Mets Hepatic adenoma Hepatic AV malformation (Osler Weber Rendu) Dysplastic Nodular Regenerative nodules Fibrolamellar HCC Peliosis Hepatitis