Specific Defenses Part 1

Question 1

Specific immunity (5)

Answer 1

Specificity
Foreign
Memory
Antigen
Specific acquired immunity

Question 2

Specificity

Answer 2

Recognize a specific foreign substance
“Non-self” or foreign
“Self” ie your own body’s cells

Question 3

Foreign

Answer 3

Bacteria, viruses, pollen, transplanted tissues

Question 4

Memory

Answer 4

If you recover from a specific infection, you are immune to it when exposed again

Question 5

Antigen (Ag)

Answer 5

Substance that stimulates an immune response

Question 6

specific acquired immunity

Answer 6

Is MEDIATED by LYMPHOCYTES
T cells
B cells

Question 7

T cells are responsible for

Answer 7

Thymus development and cellular immunity

Question 8

B cells are responsible for

Answer 8

Bone marrow development and humoral immunity

Question 9

B cells originate in the

Answer 9

Bone marrow

Question 10

B cells produce

Answer 10

Antibody molecules that recognize and bind to Ag

Question 11

T cells originate in the

Answer 11

Bone marrow

Question 12

B cells mature in the

Answer 12

Bone marrow

Question 13

T cells mature in the

Answer 13

Thymus

Question 14

T cells have what that recognizes Ag on the surface of a target cell.

Answer 14

Cell surface receptors (TCR)

Question 15

Acquired immunity is protection that developed over

Answer 15

A lifetime against a specific Ag either after infection or vaccination

Question 16

Acquired immunity can occur NATURALLY or _____

Answer 16

Artificially

Question 17

Acquired immunity can occur ACTIVELY or ______

Answer 17

Passively

Question 18

Naturally acquired active immunity

Answer 18

Person acquires immunity naturally when encounters the pathogen

Question 19

naturally acquired passive immunity

Answer 19

Natural transfer of preformed Ab from mother to fetus or infant

Question 20

Artificially acquired active immunity

Answer 20

Immunity acquired after vaccination against a specific infectious agent

Question 21

Artificially acquired passive immunity

Answer 21

Immunity acquired after injection of preformed Ab

Question 22

Active immunity happens when your own system has been activated. (T/F)

Answer 22

T

Question 23

Is active immunity long lasting?

Answer 23

Yes

Question 24

Passive immunity happens when antibodies (made somewhere else) are given to you. (T/F)

Answer 24

T

Question 25

passive immunity is short lasting (T/F)

Answer 25

T

Question 26

2 immune systems of specific acquired immunity

Answer 26

Humoral and cell mediated

Question 27

Effective against intracellular viruses, fungi, Protozoa, transplants, and cancer cells.

Answer 27

Cell mediated immune system

Question 28

Effective against extracelluar viruses, bacterial toxins and circulating viruses from floating blood and fluids.

Answer 28

Humoral immune system

Question 29

Humoral immune system is mediated by

Answer 29

Antibodies

Question 30

Cell mediated immune system is mediated by

Answer 30

Direct cell-cell interactions

Question 31

B lymphocytes are used in the ___ immune system

Answer 31

Humoral

Question 32

T lymphocytes are used in the ___ immune system

Answer 32

Cell mediated

Question 33

Do antibodies go into the cell?

Answer 33

NO, they cannot enter the cell

Question 34

Polypeptides are made of

Answer 34

Amino acids (several or more joined together)

Question 35

How many polypeptides comes together to made an antibody molecule?

Answer 35

2

Question 36

What are the chains called in an antibody molecule?

Answer 36

Heavy chains (2) Light chains (2)

Question 37

How many antigen binding sites are in a single antibody molecule

Answer 37

2 The top of the Y

Question 38

The shape of an antibody molecule

Answer 38

Y

Question 39

How many antigens can an antibody bind to inself?

Answer 39

2

Question 40

How many classes of antibodies can we recognize

Answer 40

5

Question 41

What are the classes of antibodies

Answer 41

IgG IgM IgA IgD IgE (Ig = immunoglobulin)

Question 42

IgG is the only antibody that can

Answer 42

Cross the placenta

Question 43

A protein that coats a microbe to enchace pahgo

Answer 43

Opsonin

Question 44

What class of antibody is an opsonin

Answer 44

IgG

Question 45

The main antibody we produce in a secondary immune response.

Answer 45

IgG

Question 46

The ONLY case where you DO NOT want antibodies for the pathogen.

Answer 46

HIV

Question 47

If you have a lot of IgG you are protected against the pathogen, EXCEPT for…

Answer 47

HIV

Question 48

IgM has how many binding sites?

Answer 48

10

Question 49

First antibody during a primary immune response

Answer 49

IgM

Question 50

the main antibody in secretions

Answer 50

IgA

Question 51

IgD’s function

Answer 51

Unkown

Question 52

IgE is important in defense against

Answer 52

Parasitic worms

Question 53

the main antibody produced if you allergic to something

Answer 53

IgE