Antimicrobial drugs Flashcards

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1
Q

Antibiotics are either _____ or ____.

A

Bacteriostatic or bacteriocidal

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2
Q

Bacteriostatic=

A

Inhibits bacterial growth

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3
Q

Bacteriocidal=

A

Kills bacteria

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4
Q

Ribosomes role

A

Synthesize proteins

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5
Q

Antibiotics disrupt cell _____ function.

A

Membrane

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6
Q

The membrane is made of

A

Phospholipids

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7
Q

The antibiotics that bind to cell membrane

A

Polymixins and polyenes

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8
Q

When the antibiotic binds to the cell membrane it makes it more ____ to get into the cell.

A

Permeable

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9
Q

Polyenes are used specifically against

A

Fungis

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10
Q

Penicillin, bacitracin, and cephalon sporins target what

A

The cell wall (cell wall synthesis)

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11
Q

Why won’t penicillin effect human cells?

A

Because we do not have cell walls with peptidoglycan layers.

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12
Q

What layer does penicillin target

A

Peptidoglycan

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13
Q

Quinolenes and nalioixic acids inhibit

A

Inhibition of DNA synthesis

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14
Q

Rifamycin inhibits

A

Inhibition of RNA synthesis

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15
Q

50s is targeted by

A

erythromycin and chloramphenicol

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16
Q

30s is targeted by

A

Tetracycline
Stetomycin
Gentamycin

17
Q

5 methods in which antibiotics target a cell

A

1) cell membrane
2) cell wall synthesis
3) inhibition of RNA and DNA synthesis
4) inhibition of protein synthesis
5) inhibition of folic acid metabolism

18
Q

Why are the antibiotics that target protein synthesis Bacteriostatic?

A

Because the ribosomes will not be able to make any proteins but the cell is still alive.

19
Q

PABA converts to

A

Folate

20
Q

Drugs that inhibit folic acid metabolism

A

Sulfonamides
Trimetoprim

21
Q

Do humans synthesize folic acid?

A

No, thats why sulfonamides and trimetoprim are effective.