Epidemiology and Pathogenesis Flashcards

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1
Q

Pathology

A

Scientific study of disease

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2
Q

Etiology

A

Cause of a disease

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3
Q

Pathogenesis

A

The way a disease develop (structural and functional changes)

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4
Q

infection

A

Invasion or colonization of the body by a pathogenic microbe

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5
Q

disease

A

When an infection leads to a change in normal status of health.

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6
Q

Does every infection cause disease?

A

No

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7
Q

Any organism that harbors another organism

A

Host

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8
Q

3 types of floras

A

Normal
Resident
Transient

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9
Q

Flora
Permanent; not pathogenic microogaisms

A

Normal flora

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10
Q

Flora
Always present on/in human body

A

Resident flora

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11
Q

Flora
Last few hours to few months

A

Transient flora

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12
Q

Do we have more bacteria than we do cells in our bodies?

A

Yes

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13
Q

The project to identify all the microbes found in all the different parts of the body and relationship to changes in between the microbiomes, the human body, and disease.

A

The Human Microbiome Project

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14
Q

Does keeping a healthy normal flora increase the chances of infection and disease?

A

No, it DECREASES

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15
Q

Name a sterile location in the body

A

The brain

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16
Q

Largest microbiome in the body

A

GI tract

17
Q

symbiosis

A

Associated between 2 or more species

18
Q

Commensalism

A

One organism benefits; other nor affected

19
Q

Example of commensalism

A

Staphylococcus epidermidis (on our skin)

20
Q

What usually benefits from a commensalism relationship, what do they do?

A

The normal flora usually benefits the host by preventing pathogens from overgrowing.

21
Q

Both organisms benefit

A

Mutualism

22
Q

example of mutalism

A

E.coli in intestines produces vitamin K and some B vitamins

23
Q

Competition between the microorganisms. Competitive exclusion.

A

Antagonsim

24
Q

Parasitism

A

One organism benefits, the other is harmed

25
Q

Antagonsim example

A

Clostridium difficile overgrows after antibiotic therapy

26
Q

Normal flora benefit the host by ____ ____.

A

Competitive eclusion
Whereby they prevent the overgrowth of harmful microorganisms

27
Q

Competitive eclusion has lead to the study of

A

Probiotics
Live microbial cultures are applied or ingested to cause a beneficial effect on the host

28
Q

Bacteriocins

A

Proteins secreted by E.coli in large intestine to inhibit other bacteria