Specific Antidotes Flashcards
Acetaminophen
N-acetylcysteine (replenishes glutathione)
*Sulfahydryl group supplementation*
AChE inhibitors, organophosphates
Atropine followed by pralidoxime
Amphetamines (basic)
NH4Cl (acidify urine)
Antimuscarinic, anticholinergic agents
Physostigmine salicylate, control hyperthermia
Benzodiazepines
Flumazenil
ß-blockers
Glucagon
Carbon monoxide
100% O2, hyperbaric O2
Copper, arsenic, gold
Penicillamine
Cyanide
Nitrite + thiosulfate, hydroxocobalamin
Digitalis
Anti-dig Fab fragments
Heparin
Protamine sulfate
Iron
Deferoxamine, deferasirox
Lead
EDTA, dimercaprol, succimer, penicillamine
Mercury, arsenic, gold
Dimercaprol (BAL), succimer
Methanol, ethylene glycol (antifreeze)
Fomepizole > ethanol, dialysis