Chromosomal Translocations Flashcards
1
Q
t(9;22)
A
Philadelphia chromosome
CML (bcr-abl hybrid)
2
Q
t(8;14)
A
Burkitt lymphoma (c-myc activation)
3
Q
t(11;14)
A
Mantle cell lymphoma (cyclin D1 activation)
4
Q
t(14;18)
A
Follicular lymphomas (bcl-2 activation)
5
Q
t(15;17)
A
M3 type of AML
Responsive to all-trans retinoic acid (ATRA)