Oncogenes Flashcards by Michelle Cancel | Brainscape

Q

BCR-ABL

A

CML, ALL

Tyrosine kinase

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Q

bcl-2

A

Follicular & undifferentiated lymphomas

Anti-apoptotic molecule

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Q

BRAF

A

Melanoma

Serine/threonine kinase

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Q

c-kit

A

Gastrointestinal stromal tumor (GIST)

Cytokine receptor (for stem cell factor)

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Q

c-myc

A

Burkitt lymphoma

Transcription factor

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Q

HER2/neu (c-erbB2)

A

Breast, ovarian & gastric carcinomas

Tyrosine kinase

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Q

L-myc

A

Lung tumor

Transcription factor

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Q

N-myc

A

Neuroblastoma

Transcription factor

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Q

ras

A

Colon cancer, lung cancer, pancreatic cancer

GTPase

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Q

ret

A

MEN 2A & 2B

Tyrosine kinase

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