Signaling Pathways of Endocrine Hormones

Question 1

cAMP

Answer 1

FSH, LH, ACTH, TSH, CRH, hCG, ADH (V₂ receptor), MSH, PTH, calcitonin, GHRH, glucagon

Question 2

cGMP

Answer 2

ANP, NO (EDRF)

*think vasodilators*

Question 3

IP₃

Answer 3

GnRH, Oxytocin, ADH (V₁ receptor), TRH, Histamine (H₁ receptor), Angiotensin II, Gastrin

Question 4

Steroid receptor

Answer 4

Vitamin D, Estrogen, Testosterone, T₃/T₄, Cortisol, Aldosterone, Progesterone

Question 5

Intrinsic tyrosine kinase

Answer 5

Insulin, IGF-1, FGF, PDGF, EGF

MAP kinase pathway

*think growth factors*

Question 6

Receptor associated tyrosine kinase

Answer 6

Prolactin, Immunomodulators (cytokines IL-2, IL-6, IL-8, IFN), GH

JAK/STAT pathway

*think acidophiles & cytokines*