Special care - revision notes Flashcards
What is warfarin
warfarin is a Vit K antagonsit that works by blocking the clottiginfactors essential for forming a clot.
These are clotting factors , 2, 7, 9, 10 and protein C and S
INR
international normalised ratio - measures the time for the blood to form a clot
Prothrombin time/referecne partial thromboplasatin time
PT is esseintial for forming a clot
INR for healhty people
= 1
INR for people on warfarin recienving tx
INR <4 and stable
Stable INR
<4 and has been for the last 2 months
does not require weekly monitoring
Stable INR
tests 72 hrs before the procedure
Why are people on warfarin
Atriral fibrilliation
MI
Blood clots in veins (venous thrombosis)
Blood clots in lungs (pulmonary embolism)
Low risk dental procedures
6PPC
examination
radiographs
simple XLA
RSD
direct resotrations
High risk dental procedures
Biopsies
Rasing flaps
Gingivectomy
Extensive or complicated XLA’s
Apixiban
a direct noval oral anticogulatn that works by inhibting factor Xa which works by blocking the action of activated factor xwhich is needed for forming a clot
taken x2 daily
Dabagratran
a direct inhibotr of the factor thrombin
taken x2 daily
Rivaroxaban
taken once daily
Apixaiban and dabagratran
delay morning does till haemostasis has been achied >4hrs after tx
Treatment if on warfarin
> 4 then delay treatment
early morning and week appts
haemostasiis agents ready
XLA no more than 3 teeth at one time
paracetamol instead of NSAIDs
Thrombin
convereted from prothrombin
serine protease
thrombin then converts fibrnogen to fibrin
Cogualtion casacade
for a clot to form need to activate proteins called clotting factos
- intrinsic - activated by factors in the blood (factor VII)
- extrinsic - activated by factors in the tissues
common - both theses pathways results in the activation of the common and facto X which converts fibrnogen to fibirn to form a clot
MDT for head and neck cancer
oncologist
chemo nurse
speech and language therapsit
physio
patholoigist
surgeon
speacial care dentist
Risk factors for oral cancer
smoking
acohol
betal quid
nutrtion - low in antioxidantes
Socieconmic factors
poor OH and dental health
HPV
High risk sites for oral cancer
ventral and lateral borders of tongue
buccal mucosa
floor of mouth
hard and soft palate
orpharynx
Signs and sympomts
horseness in voice
persient ulcer with unknown casues for >3wks
red or white patches in mouth >3weeks
ear pain with no ear abnormalities >3wks
persistent soreness
unexpailed lump >3wks
Clinical signs of oral cancer
solitary ulcer
raised with rolled margins
firm base and hard
erythema
Pre malgingant conditions
Leukoplakia
erythroplakia
lichen planus
palatal keratosis
squamous cell carcinoma
submucosous fibrosis
Mucosistis
inflammation and ulceration leading to pain
7-14 days after drug therapy
tx for mucositis
avoid spicy acidic food, spirits and tea
smoking avoid
soidium bicarb, tea tree oil , honey, CHX, gelclair, saline
chew on ice cubes
oral cooling ice
morphine/;laser light therapy
Radiotherapy
dose and field of tx
side effects - trismus, loss of taste, dry mouth, oral ulcers, incrseased risk of candiodsis, burning mouth, caries, osteoradnecrosis
Side effects of chemo
naseua vomiting, diarrhea
mucossitis
mouth sores dry mouth, tooth decay, bleeding
infection risk incrseaed
hair loss
fever
loss of apeptite
Chemo blood tests
white blood cells decrseased,
RBC
Platelets
Neturopenia
leukopenia
Radiation induced caries
caries that occurs at the neck of teeth due to the radiation damage casued by the radiotherapy
tx - primary rothograde surgery and decorniate
Osteoradionecrosis
damage of bone jaw
Post radio and chemo
mainitain regular dental exams
OHI and maintain good OH
High lfurodie toothpaste
Fluoride varnish
tooth mousse
saliva stimulants to help with dry mouth
stop smoking
CT vs MRI
CT - shows soft tissue and bone, quick and no claustrophibia for pt, however need blood tests to check kidneys before commening as iodine die can cause issues with kidney probs in people, small radiation risk
MRI - shows only soft tissues, non invasive, no radiation exposure, no iodine die causing issues
However - expensive, claustrophibia, takes time to do, difficult if have metal devices in body
Osteoradionecrosis
can hapen to a person after recieving radiotherapy for oral cacner
>60 grays
Signs and symptoms - pain, ulcers, sores, trismus, exposed bone, sharp pieces of bone, swelling, infection, sequestrum
Dentists before radio - remove all teeth with poor prognosis, liase with oncologist, commence all tx 10-14 days pre radio
Post radio and need tx - mayrequire hyberpbaric oxygen befroe tx
Osteroradnecrosis occurs - remove necrotic tissues, irrigation with saline, CHX mw and remove and smooth shrap edges,
only prescribe antibiotics if secondary infection occurs
Signs of oral cacern
solitary ulcer
firm and hard
raised rolled margins
erythema
Incapable means
acting
making decsion
retaining decion
understanding decision
communicaigndecsion
Who can issue a certificate of incapcity
medical practioner incharge of persons care
registered nurse
consultant in charge of pt care
dentist if specilaist training
Guardianship orders
when the person has no capacity
if have joint guardianship just need consent form 1
court appointed
requires 2medical reports
appoitned for 3years
deals with finance, proterty and martia affairs
Adults with incapacity act 2000 0or mental health act 2004 (england)
to protect people who lack capacity to make decsions and support involement in making decsions
Principles of adults with incapcity 2000 act
Beenfit
minimal intervention
takes into the wishes of the the adult
consultation with relvant others
enourages the audult to exercise residual capacity
Power of attornery
granted by the adult when thet still have capacity
certified by lawyer or by medical practioner (proxy)
Welfare - comes into affect when person incapable of making decision, realating to health and personal
Continuing power - fincial and property affairs only
Local casues of pseudomembraous candidosis
dentures - ill fitting dentures
antibiotcs
xerostomia
cortocisteriod use
General casues of psedomembranous candidosis
smoking
diabetes
cushings
iron deifiency
drugs
HIV
immunoompromised
Diseases that causes xerstomia
diabetes
radio/chemo
sjogren’s syndrome
RA
cystic fibrosis
parkinson’s disease
hyperpathyroidsm
Drugs casuing xertstome
beta blockers
antircylic antidepressants
anti convulsants
anti pysiochitoics
NSADS - diclofenac
direuetics
protein pump inhibitors
antohistamines