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Hugh's Intersystems > Soft Tissue Infections > Flashcards

Soft Tissue Infections Flashcards

1
Q

What is the species name of Grp A strep?

A

Str. pyogenes

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2
Q

What are the three techniques neutrophils use to kill pathogens?

A

Phagocytosis

Release of toxic mediators

NETs

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3
Q

What are the major gram positive bacteria that colonise the skin?

A

Staph epidermidis

Staph aurea

Diptheroids

Streptococci

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3
Q

What type of bacteria is Clostridia?

A

Gram + rods

Anaerobes

Spore-forming

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4
Q

What are the bacterial causes of impetigo?

A

Staph aureus

GAS (beta haemolytic)

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4
Q

How do you treat gas gangrene?

A

Surgery + penicillin G +/- hyperbaric O2

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5
Q

What is eczema herpeticum?

A

A primary herpes infection in patients with eczema

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6
Q

What is the species name of grp B strep?

A

Str. agalactiae

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6
Q

What do you treat diabetic foot infections with?

A

Co-amoxyclav and metronidazole

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8
Q

What is impetigo?

A

A spreading infection of the epidermis

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9
Q

What is the most common cause of folliculitis and abscess?

A

Staph aureus

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10
Q

What does saprophyticus predominantly infect?

A

Urinary Tract

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11
Q

What are the predominant bacterial causes of skin infections?

A

Staph aureus

Strep. pyogenes

clostridia

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12
Q

What pathogens has M-protein?

A

Grp A strep (pyogenes

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13
Q

How do you treat abscesses?

A

Drain them

Consider oral antibiotics

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14
Q

How does GAS cause damaged?

A

Cytolethal toxins and enzymes

Superantigens

Activation of autoimmunity

15
Q

Why is S. aureus such a successful skin pathogen?

A

It has a plethera of virulence factors that allows it to avoid the neutrophil response

16
Q

What is folliculitis?

A

Infection of hair follicle

18
Q

What biochemical factor is characteristic of S. aureus?

A

It is coagulase positive

19
Q

What do you treat impetigo and cellulitis with?

A

Flucloxacillin or dicloxacillin

21
Q

What are two type of localised bacterial infections?

A

Folliculitis

Abscess

22
Q

What is the difference between erysipelas and cellulitis?

A

Cellulitis has a similar presentation but also involves subcutaneous fat

23
Q

What is erysipelas?

A

Rapidly spreading superficial erythematous infection with well-defined borders, plus pain and fever

24
Q

What 2 types of fungi cause skin and soft tissue infections?

A

Dermatophytes

Yeasts

25
Q

What is CHIPS?

A

Virulence factor that blocks complement receptor to inhibit chemotaxis

26
Q

What are the different ways in which impetigo can present?

A

Bullous

Crusted

Pustular lesions

Hugh's Intersystems (15 decks)

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