Skin Histology and Pathology Flashcards

1
Q

What are the extentions of dermis that lie between the rete ridges called?

A

Dermal papilla

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2
Q

Who has more melanocytes, black people or caucasians?

A

They have the same number, however black people produce more melanin

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2
Q

Are Meissner or Merkel sensory receptors located in the epidermis?

A

Merkel

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3
Q

How long it take for a keratinocyte to replicate and eventually be sloughed off the epidermis?

A

60 days

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3
Q

What is the major difference between healing by primary intention and healing by secondary intention?

A

In primary intention, the edges of the epidermis are opposed easing the healing process

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3
Q

What are the three phases of healing in healing by primary intention?

A

Inflammation

Proliferation

Maturation

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4
Q

What are keloid scars due to?

A

Excessive collagen formation

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5
Q

Is there pain in full thickness burns?

A

No, due to loss of pain receptors

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6
Q

What is characteristic of the stratum spinosum?

A

Intercellular bridges

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7
Q

How long does it take for the mature scar to form in healing by primary intention?

A

6-8 weeks

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8
Q

Where the vascular plexi of the skin located?

A

The papillary plexus is located in the dermis at the border of the epidermis

The cutaneous plexus is located in the hyperdermis, at its border with the dermis

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9
Q

Where in the skin are sweat follicle located?

A

In the dermis

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10
Q

Where in the skin are hair follicles located?

A

Base of dermis or subcutaneous tissue

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11
Q

What are tonal fibrils?

A

Cytokeratin in the cytoplasm of stratun spinosum cells that insert into dermosomal junctions

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13
Q

Where is melanin located within keratinocytes?

A

External to the nucleus to protect if from UV radiation

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15
Q

How do you identify cells of the stratum granulosum?

A

By the presence of purple granules within their cytoplasm

16
Q

What are the two layers of the dermis and how do they differ from each other?

A

Papillary layer with fine collagen bundles and lots of elastin (more superficial)

Reticular layer with deeper, thicker and more course collagen bundles. Immune cells are highly prevalent

17
Q

What is the function of Merkel cells?

A

These are neuroendocrine cells that secrete humours that function in a paracrine manner. They are involved in the sensation

18
Q

What tissue are adnexal tumours derived from?

A

Sweat glands

Hair follicles

Sebaceous glands

20
Q

What are the layers of the epidermis, from deep to superficial?

A

Stratum basale

Stratum spinosum

Stratum granulosum

Stratum corneum

21
Q

Describe the appearance of sebaceous gland cells

A

Foamy due to their high lipid content

22
Q

How do the hair follicles of the scalp differ from the rest of the body?

A

They are deeper

23
Q

Where are apocrine sweat gland located?

A

Groin

Axilla