Blood Flashcards
How many RBCs are they per litre?
3-5x10^12
How often are RBCs replaced?
120days
Apart from bone marrow, where else does haemopoiesis occur?
Liver and spleen in the first 6weeks to 7months of life
Why can bone marrow transplants be given intravenously?
Because the bone marrow stroma is continuous with the systemic circulation and adhesion factors will capture infused cells
How often are platelets replaced?
Every 10 days
Which mature blood cells are myeloid in origin?
The granulocytes
Monocyte
Erythrocytes
Platelets
How often are WBCs replaced?
Every 3-5 days
What determines whether developing cells are released from the bone marrow?
Adhesion molecules
Does a growth factor cause the same effects on all of its target cell population?
No, the same growth factor can have different effects depending on the developmental stage of the cell
In which bones does most haemopoiesis occur in adults?
Axial skeleton: Pelvis, vertebrae, strenum and ribs
What are the three most important haematinics?
Iron
Vitamin B12
Folate
What is PICA?
Eating dirt and paper and similar material. Due to iron deficiency
How much WBCs are there per litre?
2-6x10^9
What are the granulocytes?
Neutrophil
Basophil
Eosinophil
How many platelets are there per litre?
150-400x10^9
