Soft skin tissue infection Flashcards

1
Q

Purulent infections

A

Furnucles
Carbuncles
Cutaneous

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2
Q

Purulent Mild Treatment

A

Incision & Drainage

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3
Q

Purulent Moderate Treatment

A

Incision & Drainage
Culture & Sensitivity
Antibiotics

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4
Q

True or False. Antibiotics are required for Mild Purulent Infections

A

False

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5
Q

Empiric ABx for Moderate Purulent SSTIs

A

TMP/SMX
Doxycyclines

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6
Q

Defined ABx for Moderate Purulent SSTIs

A

MRSA: TMP/SMX
MSSA: Dicloxacillin or Cephalexin

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7
Q

True or False. Antibiotics for Moderate Purulent SSTIs are Oral

A

True

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8
Q

What qualifies as Mild Purulent SSTIs?

A

Purulent infection WITHOUT systemic signs of infection

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9
Q

What qualifies as Moderate Purulent SSTIs?

A

Purulent infection with systemic signs of Infection

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10
Q

What qualifies as Severe Purulent SSTIs?

A

Patients who have failed I&D + Oral ABx
Septic patients
Immunocompromised patients

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11
Q

SIRS criteria

A

Systemic Inflammatory Response Syndrome
(at least 2)

-Temp >38 C or <36 C
-Tachypnea >24 breaths/min
-Tachycardia >90 beats/min
-WBC >12,000 or <4,000

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12
Q

True or False. Antibiotics for Severe Purulent SSTIs are oral.

A

False.
They are IV

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13
Q

Empric ABx for Severe Purulent SSTIs

A

Vancomycin
Daptomycin
Linezolid
Televancin
Ceftaroline

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14
Q

Defined ABx for Severe Purulent SSTIs

A

MRSA: Vanco/Dapto/Linezo/Televancin/Ceftaroline

MSSA: Nafcillin, Cefazolin, Clindamycin

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15
Q

IV MRSA ABx for SSTIs

A

Vancomycin
Daptomycin
Ceftaroline
Dalbavancin/Oritavancin

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16
Q

Oral MRSA ABx for SSTIs

A

TMP/SMX
Doxycycline
Linezolid

17
Q

IV MSSA ABx for SSTIs

A

Ampicillin/Sulbactam
Nafcillin/Oxacillin
Cefazolin

18
Q

Goal for Vancomycin IV (SSTIs)

A

Trough 10 - 15 mcg/ml

19
Q

True or False. Mild Non-Purulent Treatment requires Antibiotics.

A

True. Oral ABx

20
Q

Mild Non-Purulent Antibiotics

A

Penicillin
Cephalosporin
Dicloxacillin
Clindamycin

21
Q

Moderate Non-Purulent Antibiotics

A

Penicllin
Ceftriaxone
Cefazolin
Clindamycin

***IV

22
Q

Severe Non-Purulent Treatment

A

Antibiotics
Rule out necrotizing process
Culture and Sensitivity

23
Q

Severe Non-Purulent Empiric Antibiotics

A

Vancomycin + Piperacillin/Tazobactam

24
Q

Severe Non-Purulent Defined Antibiotics fpr Monomicrobial

A

Strep. Pyogenes: Penicillin + Clindamycin
Clostridial sp: Penicillin + Clindamycin
Vibrio Vulnificus: Doxycycline + Ceftazdime
Aeromonas hydrophilia: Doxycycline + Ciprofloxacin

25
Q

Severe Non-Purulent Defined Antibiotics for Polymicrobial

A

Vancomycin + Piperacillin/Tazobactam

26
Q

True or False. Both purulent and non-purulent SSTIs are exudatous

A

True

27
Q

Bacterial species in Purulent SSTIs

A

Staphylococcus Aureus

28
Q

Bacterial species in Non-Purulent SSTIs

A

Streptococcus

29
Q

True or False. Drainage and culture is recommended for cellulitis

A

False.
Blood cultures recommended though

30
Q

Treatment for Necrotizing Fascitis

A

SURGERY
blood cultures and deep tissue cultures
Start broad spectrum ABx empirically

31
Q

What Antibiotics to start empirically for Necrotizing Fascitis?

A

Vancomycin + Piperacillin/Tazobactam

32
Q

Treatment duration for Necrotizing Fascitis

A

No definite answer
Continue ABx until:
- debridement no longer needed
- Patient clinically improves
- Afebrile for 48 - 72 hours

33
Q

Diabetic Foot Infection- why do they happen?

A

Neuropathy
Vascular disease
Immune modulation

34
Q

How does diabetic foot infection clinically present?

A

From ulcer/wound from trauma
Red, warm, tender, purulent
charcot foot
may probe to bone, foreign body, abscess
>2 - wounded infection

35
Q

DFI Mild classification

A

Erythema >0.5 cm but < 2cm

36
Q

DFI Moderate Classification

A

Erythema >2 cm or with structures deeper than the skin

37
Q

DFI Severe Classification

A

Erythema >2 SIRS criteria

38
Q

True or False. For Diabetic Foot Infection, you must culture a clinically uninfected wound.

A

False. Do NOT culture a clinically uninfected wound.

39
Q

Are cultures for moderate and severe DFIs essential?

A

Yes