Antibiotics classes Flashcards

1
Q

Penicillins

A

Penicillins

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2
Q

Penicillin MOA

A

binds to transpeptidase enzymes in cell wall and disrupt cell wall formation

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3
Q

Cephalosporins

A

1st gen: Cephalexin, Cefazolin
2nd gen: Cefuroximine
3rd gen: Ceftazidine
4th gen: Cefepime
5th gen: Cefepime

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4
Q

Cephalosporin MOA

A

bind to transpeptidase enzyme and disrupt cell wall formation

***Bacteriacidal

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5
Q

Aminoglycosides

A

Gentamicin
Tobramycin
Amikacin

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6
Q

Aminoglycosides MOA

A

bind to 30s ribosomal subunit and inhibit bacterial protein synthesis

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7
Q

Tetracyclines

A

Tetracycline and Doxycycline

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8
Q

Tetracyclines MOA

A

reversibly bind to 30s ribosomal subunit to inhibit bacterial protein synthesis

***Bacteriostatic

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9
Q

Macrolides

A

Erythromycin
Azithromycin
Clarithromycin

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10
Q

Macrolides MOA

A

reversibly bind to 50s ribosomal subunit and inhibit bacterial protein synthesis

***Bacteriostatic

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11
Q

Lincosamides

A

Clindamyacin

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12
Q

Lincosamides

A

Reversibly bind to 50s ribosomal subunit and inhibit bacterial protein synthesis
-bone penetration

***Bacteriostatic

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13
Q

Fluroquinolones

A

Ciprofloxacin
Levofloxacin
Moxifloxacin

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14
Q

Fluroquinolones MOA

A

inhibit DNA gyrase to cause DNA breakage

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15
Q

Glycopeptides

A

Vancomycin

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16
Q

Glycopeptide (Vancomycin) MOA

A

bind to d-alanyl-d-alanine in the growing peptidoglycan chain

***Bacteriocidal

17
Q

Lipopeptide

A

Daptomycin