Antibiotics classes Flashcards
Penicillins
Penicillins
Penicillin MOA
binds to transpeptidase enzymes in cell wall and disrupt cell wall formation
Cephalosporins
1st gen: Cephalexin, Cefazolin
2nd gen: Cefuroximine
3rd gen: Ceftazidine
4th gen: Cefepime
5th gen: Cefepime
Cephalosporin MOA
bind to transpeptidase enzyme and disrupt cell wall formation
***Bacteriacidal
Aminoglycosides
Gentamicin
Tobramycin
Amikacin
Aminoglycosides MOA
bind to 30s ribosomal subunit and inhibit bacterial protein synthesis
Tetracyclines
Tetracycline and Doxycycline
Tetracyclines MOA
reversibly bind to 30s ribosomal subunit to inhibit bacterial protein synthesis
***Bacteriostatic
Macrolides
Erythromycin
Azithromycin
Clarithromycin
Macrolides MOA
reversibly bind to 50s ribosomal subunit and inhibit bacterial protein synthesis
***Bacteriostatic
Lincosamides
Clindamyacin
Lincosamides
Reversibly bind to 50s ribosomal subunit and inhibit bacterial protein synthesis
-bone penetration
***Bacteriostatic
Fluroquinolones
Ciprofloxacin
Levofloxacin
Moxifloxacin
Fluroquinolones MOA
inhibit DNA gyrase to cause DNA breakage
Glycopeptides
Vancomycin