Immunizations Flashcards
Live Vaccinations
MMR
Varicella
Zoster
Rotavirus
LAIV
Poilo (OPV)
Toxoid Vaccinations
Diphtheria
Tetanus
Inactivated
Influenza
Polio (IPV)
Pertussis
Hep A
Recombinant Vaccines
Hep B
HPV
RZV (Recombo Zoster Vax)
Conjugated/Polysaccharide Vaccines
Hib
Meningococcal
Pneumococcal
Vax rate for herd immunity for Measles
83% - 94%
Vax rate for herd immunity for Pertussis
92% - 85%
How long should you wait between live vaccines if not given simultaneously?
28 days
What does a decrease in dosing interval do to the live vaccine efficacy?
It decreases AB response and protection
What does an increase in dosing interval do to live vaccine efficacy
It delays protection
True or False. You have to readminister vaccine dose if greater than 5 days before the minimum dosing interval
True
What vaccines are contraindicated in pregnancy
HPV
Live vaccines (MMR, Varicella)
What vaccines can you give in pregnancy?
Tdap
COVID-19
Inactivated Flu (Season (October - April)
How long should you wait to dose live vaccines during chemo/radiation?
2 weeks before
OR
3 months after
How long should you wait to dose live vaccines with systemic corticosteroids <14 days?
immediately after or 2 weeks
How long should you wait to dose live vaccines with systemic corticosteroids >14 days?
wait 1 month post-steroid therapy
What steroids can you take with live vaccines?
Topical or local injection steroids
physiological maintenance steroids
low dose systemic corticosteroids
What constitutes high dose steroids?
> 2mg/kg/day
OR
20 mg/day
When should you postpone an immunization?
Mod-severe illness (Hospitalized)
Hx of anaphylaxis w/ vax
Immunosuppressed
If you
If you give an IVIG vaccine and a live vaccine within 14 days, what should you do?
RE-administer live vaccine
When should you give a live vaccine post IVIG?
3 months post IVIG
If patient has Kawasaki disease and given IVIG, how long should you wait to give live vaccines?
11 months
How long should you wait after live vaccine to give PPD Skin test?
4 - 6 weeks
How long should you avoid antivirals for after live vaccine?
14 days
Which vaccines can be give SQ
MMRV
PPSV23
Meningococcal Polysacch (MPSV-4)
Herpes Zoster (Zostavax)
Polio trivalent (inactive)
Which vaccine can be given SQ and IM
Polio trivalent (inactivated)
Pfizer vaccine for ages 6 months - 4 years
(mono and bi)
maroon cap
Pfizer vaccine for ages 5 - 11 years
(mono and bi)
orange cap
Pfizer vaccine for ages 12 years and up
(mono and bi)
gray cap
Moderna vaccine for ages 6 months - 5 years (monovalent)
blue cap and magenta label
Moderna vaccine for ages 6 months - 5 years (bivalent)
dark pink cap, yellow label
Moderna vaccine for ages 6 - 11 years (monovalent)
blue cap, purple label
Moderna vaccine for ages 6 - 11 years (bivalent)
blue cap, gray label
Moderna vaccine for ages 12 years and up (monovalent)
red cap, blue label
Moderna vaccine for ages 12 years and up (bivalent)
blue cap, gray label
Pfizer storage in ultra cold freezer?
Until Exp
Pfizer storage in refrigerator?
10 weeks
Pfizer storage at room temp?
12 hours
Moderna storage in freezer
until exp
Moderna storage in refrigerator?
30 days
Moderna storage at room temp?
24 hours (8 hours if punctured)
Antigenic what causes pandemic and epidemics?
Antigenic shift
Antigenic what causes a yearly change in vaccines?
Antigenic drift
Antigenic shift is type(s)?
Type A
Antigenic drift is type(s)?
Type A and B
What changes in Antigenic shift?
Hemagluttinin and neuraminidase
How long does it take for onset of influenza vaccine immunity
2 weeks
What is the median influenza vaccine efficacy?
47% (varies based on age)
What is the pneumococcus vaccine regimen?
PCV20
OR
PCV15 followed by PPSV23 after 1 year
True or False. Herpes Zoster presents as a bilateral painful rash
False. Unilateral painful rash
Which groups of people receive herpes zoster vaccine?
> 50 years old
AND
19 year olds and immunocompromised
What are the risk types for rabies vaccine?
Unprovoked vs provoked
AND
Type of animal
Rabies Post-Exposure Prophylaxis
Wound cleansing
Human Rabies IG via IM
4 doses of vaccine (day 1, 3, 7, 14)
Rabies pre-exposure prophylaxis
Just the vaccine