SNPs Flashcards
FUT2
Vit B-12, H.Pylori, Celiac, risk of low B-12
VDR
Vit D Receptors, calcitriol, calbindin. Bones! Boney fish, vit D. micros
SOD2
Mitochondria. Oxidation, inflammation & OS disease, can’t make antioxidants, ITVN: manganese, glut
LCT
Lactase gene, can’t make it. Swap, enzyme
MCM6
Before LCT, “rope”. Upstream of lactase gene. No dairy, lactase enzyme
Methyl Group
Carbon w 3 hydrogens
Methyltransferase
Enzyme moves methyl group
CYP1A2
slower caffeine metabolism. Drink less/earlier
APOE (1-4)
Lipids in brain. Fish oil
CBS
homocysteine into cystathionine. Cysteine, remove sulfur. IntvN: increase b 6, methionine
COMT
Inactivates dopamine, epinephrines in brain. Ensures constant, normal levels but can work too rapidly or slowly causing behavioral changes. ITVN: B6, Mg
FTO
Obesity gene
GAD1
glutamtate-GABA. sedative, deep sleep. Low levels=insomnia.
MAOA
Break down of neurotransmitters. adrens, serotonins, dop. Regulates mood. Low-more aggression, altered emo learning. ITVN: B2
MTHFR
folate, folic acid, DNA, RNA. C677T
PEMT
PE-PC in liver. Starvation, homocysteine, MTHFR. ITVN: Choline, Sam-e, green tea.
UDP
feces, urine toxin. crigler-najjar syndrome, gilbert syndrome
SULT
Detox carcin/tox, lung cancer, sulfur
NAT
carcin, durgs, poor met, hepotox, cancer