Small Intestine Disorders Flashcards
1
Q
What are the symptoms of small intestinal disorders?
A
Weight Loss Increased appetite Diarrhoea Usually watery Sometimes steatorrhoea Bloating Fatigue
2
Q
What is a skin manifestation of coeliac disease?
A
Dermatitis Herpetiformis (IgA deposit on skin)
3
Q
What is coeliac disease?
A
Systemic autoimmune disorder triggered by glucose peptides from wheat and grains.
Partial or subtotal villous atrophy
Increased intra-epithelial lymphocytes
4
Q
What investigations should be done to diagnose coeliac disease?
A
FBC and blood smear
Immunoglobulin A-tissue transglutaminase (IgA-tTG)Endomysial antibody (EMA)
skin biopsy
IgG DGP (deamidated gliadin peptide) or IgA/IgG DGP
IgG-tTG
Small bowel - macroscopic
HLA Typing
