Hepatitis

Question 1

Which viral hepatitis’ are acute, self limiting enteric viruses?

Answer 1

A and E

Question 2

Which viral hepatitis’ are chronic and parenteral diseases?

Answer 2

B, C and D

Question 3

How is Hepatitis A spread?

Answer 3

Faecal-oral
Sexual
Via blood

Question 4

What is the presentation of Hep A stools?

Answer 4

Clay coloured

Question 5

How is Hep A diagnosed?

Answer 5

IgM anti Hepatitis A Virus antibody (also IgG)

Question 6

Who should get vaccinated against Hep A?

Answer 6

Travellers
Patients with chronic liver disease
Haemophiliacs
Occupational exposure-lab workers
Men who have sex with men (MSM)

Question 7

What are the four Hep B antigens and what does their presence indicate about the disease?

Answer 7

Hepatitis surface antigen (HBsAg)-Presence of virus
Hepatitis e antigen (HBeAg) -Active replication
Hepatitis core antigen (HBcAg)-Active replication (not detected in blood)
HBV DNA-Active replication

Question 8

What are the four Hep B antibodies and what do they indicate about the disease?

Answer 8

Anti-HBs - Protection
IgM anti-HBc-Acute infection
IgG anti HBc-Chronic infection/exposure
Anti-HBe - Inactive virus

Question 9

What is the treatment for Hepatitis B?

Answer 9

Pegylated interferon

Oral antiviral drugs-lamivudine, entecavir and adefovir

Question 10

In what patients is the resistant RNA virus Hepatitis D found?

Answer 10

Hep B patients- co infection

Question 11

What is the treatment for autoimmune hepatitis?

Answer 11

Azathioprine