Acute GI Bleed Flashcards
What is the landmark that separates upper and lower GI tract?
Ligament of Trietz
What are some causes of upper GI bleeds?
Oesophageal ulcer Oesophagitis Stomach Gastric ulcer Gastritis Duodenum Duodenal ulcer Duodenitis Oesophageal varices Mallory Weiss Tear Oesophageal malignancy Gastric varices Portal hypertensive gastropathy Gastric malignancy Dieulafoy Angiodysplasia Angiodysplasia
What are the risk factors for peptic ulcers?
Smoking Previous history and family history of peptic ulcers H. Pylori disease NSAID use Increasing age
How does H Pylori presence cause peptic ulcers?
They produce urease so increases ammonia production. More acid secreted in response
How does NSAID use cause peptic ulcers?
Means prostaglandin production so get reduced mucous and bicarbonate excretion so defences are minimised.
What is Zollinger-Ellison syndrome?
Gastrin-secreting pancreatic tumour causes recurrent poor healing duodenal ulcers. Cancer could be sitting under ulcers so need a repeat endoscopy 8 weeks after
What is a Mallory Weiss tear?
Linear tear at oesophago-gastric junction
Follows period of retching/vomiting