Small Animal Gastric Disease

Question 1

What are some clinical signs of gastric disease?

Answer 1

Vomiting
Anorexia
Weight loss
Abdominal pain
Melena

Question 2

What is the endpoint of the vomiting reflex?

Answer 2

Vomiting center in the brain

Question 3

CRTZ (Chemoreceptor Trigger Zone) works inside or outside of the blood brain barrier?

Answer 3

Outside of the blood brain barrier

Question 4

What are 4 types of antiemetics?

Answer 4

NK-1 receptor antagonists (Cerenia)
5-HT3 receptor antagonists (ondansetron)
D2 Receptor antagonists (metoclopramide)
a2 receptro antagonists (Thorazine)

Question 5

What cells in the stomach produce gastric acid?

Answer 5

Parietal cells

Question 6

What are some causes of gastric ulceration/erosion in dogs and cats?

Answer 6

Inhibition of PH synthesis
Cox1 vs Cox2
Effect worsened by: concurrent glucocorticoids, other ulcerogenic condition

Question 7

What is the drug of choice for decreasing gastric acid levels?

Answer 7

Proton pump inhibitors (omeperazole, pantoprazole)