slide flashcards W2D2

1
Q

what is dale’s law

A

that each neuron specializes and synthesizes only one neuron (WRONG)

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2
Q

what does it mean if a neuron is serotogenic

A

produces serotonin, does NOT mean that it has serotonin receptors or only responds to serotonin

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3
Q

what does it mean if a neuron is dopamegenic

A

produces dopamine, does NOT mean that it has dopamine receptors or only responds to dopamine

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4
Q

true or false: neurotransmitters are taken up by receptors/receiving neuron

A

FALSO

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5
Q

what protiens bring vesicles carying neurotransmitters to cell membrain to be released into synapse

A

snare protiens

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6
Q

what is clathrin and what does it do

A

protien that reuptakes/recycles vesicles (similar to transporter protiens and neurotransmitters)

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7
Q

ligand (def)

A

something that binds to a receptor

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8
Q

exogenous (def)

A

made outside of the body (foreign)

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9
Q

endogenous (def)

A

made inside the body

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10
Q

name the catecholamines

A

dopamine, epinephrine, norepinephrine

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11
Q

name the indoleamine(s)

A

serotonin

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12
Q

name the imidazoleamine(s)

A

histamine

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13
Q

name the amino acid neurotransmitters

A

glutamate, aspartate, GABA, glycine

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14
Q

name the peptide neurotransmitters

A

opiodes, vasopressin, oxytocin

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15
Q

name 3 atypical neurotransmitters

A

anandamide, nitric acid, carbon monoxide

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16
Q

what causes a neuron to release peptides in addition to neurotransmitters

A

HIGH firing rate (this is REALLY important info)

17
Q

name the neuromodulators

A

acetylcholine, dopamine, serotonin

18
Q

process of acetylcholine synthesis + degradation

A

choline + acetylCoA——–ChaT enzyme——–acetylcholine——-AChE enzyme—-choline + acetyleCoA

19
Q

order of catecholamine synthesis

A

tyrosine—–TH enzyme——-L-dopa——enzyme—–dopamine—-enzyme—-norepinephrine——enzyme—–epinephrine

20
Q

what does dopamine ‘deal with’

A

reward, working memory/planning, motor innitiation + termination

21
Q

what does norepinephrine ‘deal with’

A

allertness, mood, sympathetic activation

22
Q

what does epinephrine ‘deal with’

A

mood, agression, obsessive/compulsive behaviors, anxiety, sleep, pain

23
Q

name the 3 dopamine pathways

A

nigrostriatal, mesolimbic, and mesocortical pathways

24
Q

the BLANK (movement) pathway sends dopamine to BLANK and is associated with BLANK disease

A

nigrostriatal pathway sens dopamine to the midbrain and is associated with parkinsons disease

25
Q

the BLANK (drug reward) pathway sends dopamine to BLANK and is associated with BLANK SYMPTOMS of BLANK disease

A

the mesolimbic pathway sends dopamine to forebrain and is associated with positive symptoms of skitzofrenia

26
Q

the BLANK (executive functioning) pathway sends dopamine to BLANK and is associated with BLANK SYMPTOMS of BLANK disease

A

the mesocortical pathway sends dopamine to prefrontal cortex and is associated with negative symptoms of skitzophrenia

27
Q

where is the substantia nigra

A

midbrain, above crus cerebri

28
Q

which dopamine pathway(s) starts at the substantia nigra and where does it go

A

the nigrostriatal pathway starts at the substantia nigra and sends dopamine to the midbrain

29
Q

which dopamine pathway(s) starts at the ventral tegmental area and where does it go

A

the mesolimbic and mesocortical pathways start at the ventral tegmental area/midline/midbrain and send dopamine to the forebrain and prefrontal cortex respectivly