Sleep Related Movement Disorders

Question 1

Difference between hypnic jerks and propiospinal myoclonus?

Answer 1

Hypnic jerks involve simultaneous contractions of axial muscles occuring during quiet wakefulness

propiospinal myoclonus involves propagation across adjacent spinal segments. It usually starts in the midthoracic segments and then slowly propagates up and down into the spinal cord, resulting in repetitive and irregular jerky flexion, or extension of the trunk, neck, knees and hips.

They both occur in sleep to N1 transition

Question 2

Medications that ALMAs are associated with?

Answer 2

antidepressants

Question 3

What is Benign Sleep Myoclonus of Infancy
- starts and ends?
- how to differentiate it from epilepsy

Answer 3

observation of repetitive myoclonic jerks that involve the limbs, trunk, or whole body only during sleep. It starts in early infancy, birth to 6 months of age. Movements stop when the baby wakes up, though it is often confused with epilepsy. Unlike the jerks of myoclonic seizures or myoclonic encephalopathy, these occur exclusively during sleep

Ends at one year

Question 4

Chin activity during PSG in bruxism is how much more than baseline?
What stage of sleep is bruxism more common

Answer 4

2x more than baseline
NREM sleep has more bruxism

Question 5

Key feature of sleep related repetitive rhythmic movement disorder (SRRMD)
What are the ages affected?

Answer 5

It has to results in difficulty sleeping or impaired daytime functioning
Present from 9 months to 10 years

Question 6

What kind of iron therapy is best for RLS

Answer 6

Ferric carboxymaltose

Question 7

What is gabapentin enacarbil and what does it treat?

Answer 7

Prodrug to gabapentin
Treats RLS
side effect can be suicidality like all other AEDs