Sleep Flashcards

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1
Q

How is sleep defined?

A

Sleep remains the only universal behaviour known to biology with no clear consensus regarding a fundamental underlying function.

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2
Q

What do the different volumes of sleep mean about the animal?

A

The safer the animal feels the more sleep they have. Vulnerable animals will sleep very little and be easily aroused.

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3
Q

How long will a dolphin or whale stay awake for after giving birth?

A

24 hours a day for the first couple of weeks while the baby is particularly vulnerable.

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4
Q

How long will male sandpipers stay awake during spring breeding season?

A

active up to 23hours a day for nearly 3 weeks.

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5
Q

What is the function of hibernation?

A

Conserving energy while food is scarce.

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6
Q

What physiological things happen to an animal during hibernation?

A

Heart rate decreases and dendrites lose almost a quarter of their branches.

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7
Q

What is unihemispheric sleep?

A

One hemisphere (and the opposite eye) sleeps while the other remains awake.

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8
Q

What animals does unihemispheric sleep occur?

A

Aquatic mammals e.g. dolphins and many birds, and some reptiles.

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9
Q

What sleep waves occur during unihemispheric sleep?

A

Only slow-wave sleep (not REM sleep) occurs.

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10
Q

What is the inactivity theory?

A

The adaptive or evolutionary theory. Suggests inactivity at night helped animals survive as they did not injure themselves in the dark and were not killed by predators. This was therefore a trait passed on through natural selection.

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11
Q

What is a limitation of the inactivity theory?

A

Its always safest to be conscious, even if lying still in the dark.

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12
Q

What is the energy conservation theory?

A

Food is not always easy to come by, so an animal must conserve its energy. This is especially important during the night when it may be harder to find food.

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13
Q

What support is there for the energy conservation theory?

A

Support: energy metabolism is reduced during sleep (10% in humans and more in other species).

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14
Q

What limitations are there for the energy conservation theory?

A

Animals engaging in unihemispheric sleep are still using up energy.

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15
Q

What is the Restorative Theories?

A

During sleep there is restoration of what has been lost from the body whilst awake (e.g., muscle mass, tissue cells).

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16
Q

What support is there for the restoration theory?

A

Many major restorative functions (e.g., muscle growth, tissue repair) occur mainly in sleep.

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17
Q

What is the brain plasticity theory?

A

Sleep is a time in which the brain develops and changes i.e. creating new neurone and pruning old connections.

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18
Q

What support is there for the brain plasticity theory?

A

Sleep appears to be crucial for initial brain development in infants. Extensive research to suggest improvement in cognitive function (especially memory) following sleep.

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19
Q

What is circadian rhythms?

A

The human biological clock - like that of most organisms - synchronises to the Earth’s 24 hour rotation using signals from the environment, known as zeitgebers (time-giver).
Light is the strongest zeitgeber, although social cues also have an influence e.g. getting used to waking up at certain times.

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20
Q

Circadian rhythms: What will happen to your body in the morning when not slept all night?

A

After an entire night without sleep you will still begin to feel more alert in the morning when it becomes light.

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21
Q

Circadian rhythms: When there is no reason to wake at a specific time, what happens to peoples waking times in e.g. Germany?

A

People on the eastern edge will wake 30 mins earlier than people on the western edge consistent with the 30 mins sun difference timing.

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22
Q

What are ‘morning larks’?

A

Morning people. Wake early, alert, and reach their peak of productivity early.

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23
Q

What are ‘night owls’?

A

Evening people, take longer to warm up, reach their productivity later.

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24
Q

What are the downfalls of being a night owl in a morning lark world?

A

Lower grades, increased alcohol use, less happy overall.

25
Q

Mammalian cells contain “circadian clocks”, what are these?

A

Collections of genes which regulate the switching on of other genes critical for cell physiology and metabolism.

26
Q

What does damage to the suprachiasmatic nuclei cause?

A

Causes the peripheral clocks to lose their rhythmicity.

27
Q

What does the pineal gland secrete?

A

Melatonin, a hormone that increases sleepiness.

28
Q

How does melatonin feed back to reset the biological clock?

A

Through its effects on the receptors in the suprachiasmatic nucleus.

29
Q

What can melatonin taken in the afternoon do for sleep?

A

It can phase advance the internal clock being used as a sleep aid.

30
Q

What is the brainstem responsible for?

A

Mediating levels of arousal - including the cycle of Non-REM and REM sleep.

31
Q

What does stimulation of the pontomesencephalon do?

A

Wakes someone when they are sleeping to increases alertness in someone who is already awake

32
Q

How does a polysomnograph work?

A

It uses electrodes to record a combination of eye movement activity and EEG

33
Q

What is stage 1 of sleep and what does the EEG show during it?

A

The transition period between sleeping and waking.

The EEG is dominated by irregular, jagged, low-amplitude waves of different frequencies.

34
Q

What does stage 2 sleep show on an EEG?

A

Characterised by sleep spindles and K-complexes.

35
Q

What physiological changes happen during stage 3 and 4 sleep?

A

Heart rate, breathing rate and brain activity decrease.

36
Q

What does the EEG look like in stage 3 and 4 sleep?

A

Slow frequency (delta, 1-3hz), large amplitude waves become more common.

37
Q

In stage 3 and 4 sleep, what happens to the neurons in the neocortical layers during slow wave sleep?

A

nearly all neurone in all neocortical layers are silent simultaneously.

38
Q

What does the EEG show during stage 5 (REM) sleep and what does this indicate?

A

irregular, low amplitude, high frequency oscillations indicating increased neuronal activity which suggests lighter sleep.

39
Q

What physical features happen during REM sleep?

A

Postural muscles in the body are more relaxed, higher variability of heart and breathing rate, erections/vaginal moistening and facial twitches.

40
Q

What neuron is responsible for initiating REM and NREM sleep?

A

GABAergic neurone from the medulla

41
Q

Name 3 sleep disorders

A

Narcolepsy, REM Behaviour disorder and sleep and violence.

42
Q

What is narcolepsy?

A

A condition characterised by frequent periods of sleepiness during the day. it has a Clear genetic component.

43
Q

What are the 4 main symptoms of narcolepsy?

A

Attacks of sleepiness during the day, occasional cataplexy, sleep paralysis and hypogogic hallucinations.

44
Q

What cell do people with narcolepsy lack?

A

Hypothalamic cells that produce and release orexin - potentially due to an auto-immune condition.

45
Q

Why cant orexin be administered to narcolepsy sufferers?

A

It cannot cross the blood-brain barrier.

46
Q

How is narcolepsy mainly treated?

A

With stimulants e.g. Ritalin.

47
Q

What is REM Behaviour Disorder (RBD)?

A

People with REM disorder move around vigorously during REM, often violently. They frequently injure themselves, others or damage property.

48
Q

What disease is RBD strongly associated with ?

A

Parkinsons disease and also thought to be a very early pre-curser to the condition.

49
Q

What is sleepwalking?

A

Complex movements carried out during sleep, sometimes dangerous. e.g., eating, rearranging furniture, driving cars, walking long distances

50
Q

What stage(s) of sleep does sleep walking occur?

A

NREM sleep, could not occur during REM due to muscle atonia.

51
Q

What are the risk factors of sleepwalking?

A

sleep deprivation, stress, alcohol

52
Q

Who sleep walk?

A

Anyone can sleep walk but it runs in families and occurs mainly in children.

53
Q

What is the approximate percentage of prevalence of sleep related violent behaviours?

A

2%

54
Q

What is an inadvertent murder or suicide referred to rather than RBD?

A

NREM parasomnia

55
Q

Violence during sleep: what are RBD episodes more likely to lead to?

A

Spousal injury during dreamed attack.

56
Q

What physiological factors does sleep deprivation have a direct effect on?

A

Senses, thoughts, emotions and the brain.

57
Q

What are the 4 different ways we can study sleep deprivation?

A

Experimentally depriving humans of sleep, experimentally depriving animals of sleep, examining case studies and examining sleep disorders e.g. insomnia.

58
Q

What are the effects of sleep deprivation on the brain?

A

Reduced functional connectivity of the amygdala and executive control regions.