SLE Flashcards
1
Q
What are the possible presenting signs / symptoms of SLE?
A
Malar rash, discoid lupus, mouth ulcers, diffuse patchy alopecia
Raynaud’s phenomena
Seizures, CN abnormalities. Psychological abnormalities
Pericarditis, myocarditis, endocarditis, arterial and venous thrombosis
Arthritis, myalgia
Pancytopenia
Dysphagia, lupus peritonitis, mesenteric artery occlusion
Lupus nephritis
2
Q
What autoantibodies are present in SLE?
A
ANA
anti ds-DNA
Smith antigen
3
Q
What is the management of SLE?
A
1st line - hydroxychloroquine, cyclophosphamide, mycophenolate mofetil, azathioprine
Adjuncts - NSAIDs, steroids, rituximab, IVIG, plasmapheresis
