Bone Tumours

Question 1

How should potential bone tumours be investigated?

Answer 1

Plain x-ray
FBC
CRP
Myeloma screen
PSA
U+Es
LFTs
Biopsy
CT / MRI / PET scan for staging / looking for mets

Question 2

Describe the x-ray appearance of osteoid osteoma?

Answer 2

Lesion typically present in the long bones, consisting of a round lucency <1.5cm with a dense sclerotic central nidus

Question 3

Describe the x-ray appearance of osteoblastoma?

Answer 3

Lesion typically present in the long bones, consisting of a round lucency generally around 2-6cm with a dense sclerotic central nidus

Question 4

How is osteoid osteoma managed?

Answer 4

NSAIDs

Surgery

Question 5

In what demographic does Ewing’s sarcoma typically present?

Answer 5

Males ages 10-20 years

Question 6

Describe the x-ray appearance of Ewing’s sarcoma?

Answer 6

Lytic lesion with Moth eaten appearance

Question 7

Describe the histopathological appearance of Ewing’s sarcoma?

Answer 7

Small blue round cell tumour with clear cytoplasm

Question 8

How is Ewing’s sarcoma managed?

Answer 8

Chemotherapy
Surgery
+/- radiotherapy

Question 9

Chondrosarcoma differs from other bone tumours in that it can present at any age. T/F?

Answer 9

True

Question 10

How is chondrosarcoma managed?

Answer 10

Surgery (it is generally resistant to chemo and radio)

Question 11

Describe the x-ray appearance of giant cell tumour of bone?

Answer 11

Lytic lesion present at the epiphysis of long bones which has a soap bubble appearance

Question 12

In what demographic does osteosarcoma typically present?

Answer 12

Males in the second and third decade of life

Question 13

Describe the x-ray appearance of osteosarcoma?

Answer 13

Mottled radiolucency present at the metaphysis of long bones

Question 14

How is osteosarcoma managed?

Answer 14

Chemotherapy and surgery