Skin manifestations Flashcards

1
Q

Describe erythema nodosum

A

Painful raised lesions on shins bilaterally

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2
Q

Causes of erythema nodosum

A
NO cause
Drugs - sulphonamides, penicillin
Oral contraceptive pill
Sarcoidosis
UC and chron's
Microbiology - mycobacterium tuberculosis and group A beta haemolytic streptococci
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3
Q

Describe erythema multiforme

A

Target lesions on palms, soles and limbs

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4
Q

Describe Stevens-Johnson syndrome

A

Severe variant of erythema multiforme with fever and mucosal involvement
Due to hypersensitivity reaction to drugs - NSAIDs, allopurinol and antiepileptics

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5
Q

Describe erythema migrans

A

Initial small papule at site of tick bite
Develops into large erythematous ring with central fading lasting up to 3 months
LYME DISEASE

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6
Q

Describe erythema marginatum

A

Pink coalescent rings on trunk that come and go

Seen in rheumatic fever

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7
Q

Describe pyoderma gangrenosum

A

Nodulo-pustular ulcer
~10cm
Necrotic edge
Purulent surface

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8
Q

What is pyoderma gangrenosum associated with

A

IBD

Wegeners granulomatosis

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9
Q

Treatment for pyoderma gangrenosum

A

Oral steroids and Ciclosporin

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10
Q

What exacerbates vitiligo

A

Sunlight makes it itchy

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11
Q

Skin changes in chron’s

A

Ulcers
Erythema nodosum
Pyoderma gangrenosum

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12
Q

Skin changes in diabetes mellitus

A
Ulcers
Acanthosis nigricans (type 2 - insulin resistance)
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13
Q

Skin changes in dermatomyositis

A

Shawl sign
Heliotrope rash on eyelids
Grotton’s papules

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14
Q

Skin changes in coeliac disease

A

Dermatitis herpetiformis - itchy blisters on knees, elbows and scalp

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15
Q

Treatment for dermatitis herpetiformis

A

Responds to dapsone within 48 hours

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16
Q

Skin changes in hyperthyroidism

A

Pretibial myxoedema - red, oedematous swelling above lateral malleolus

17
Q

Skin changes in chronic liver disease

A
Palmar erythema
Koilonychia 
Leukonychia
Spider naevi
Gynaecomastia 
Jaundice 
Bruising
Scratch marks
Loss of male hair distribution
18
Q

Skin changes in malabsorption

A

Dry skin
Hyperpigmentation
Hair loss

19
Q

Describe acanthosis nigricans

A

Hyperpigmentation in areas of skin folds e.g back of neck and axilla

20
Q

Causes of acanthosis nigricans

A
Insulin resistance (DM type 2, acromegaly, PCOS)
Gastric cancer