RA Flashcards

1
Q

Describe joint involvement

A

Small joints
Symmetrical
Need at least 3 joints involved

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2
Q

Criteria to measure active disease

A
DAS-28:
Number of tender joints
Number of swollen joints
Pain score
ESR or CRP
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3
Q

Detectable antibodies

A

RF sensitive

Anti-CCP specific

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4
Q

X-ray features

A
Loss of joint space
Erosions
Soft tissue swelling
Soft bones (periarticular osteopenia)
Subluxation
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5
Q

What is Felty’s syndrome

A

RA
Splenomegaly
Neutropenia

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6
Q

Extra articular manifestations of RA

A
Skin nodules
Pleurisy
Lung fibrosis
IHD
Pericardial disease
Carpal tunnel syndrome
Scleritis
Keratoconjunctivitis sicca 
Peripheral neuropathy
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7
Q

Pharmacological management of RA

A

Early DMARDs
Biological agent if active disease with trial of 2 DMARDs
Steroids for acute exacerbations
NSAIDs for symptom relief (no effect on disease progression)

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