RA Flashcards
1
Q
Describe joint involvement
A
Small joints
Symmetrical
Need at least 3 joints involved
2
Q
Criteria to measure active disease
A
DAS-28: Number of tender joints Number of swollen joints Pain score ESR or CRP
3
Q
Detectable antibodies
A
RF sensitive
Anti-CCP specific
4
Q
X-ray features
A
Loss of joint space Erosions Soft tissue swelling Soft bones (periarticular osteopenia) Subluxation
5
Q
What is Felty’s syndrome
A
RA
Splenomegaly
Neutropenia
6
Q
Extra articular manifestations of RA
A
Skin nodules Pleurisy Lung fibrosis IHD Pericardial disease Carpal tunnel syndrome Scleritis Keratoconjunctivitis sicca Peripheral neuropathy
7
Q
Pharmacological management of RA
A
Early DMARDs
Biological agent if active disease with trial of 2 DMARDs
Steroids for acute exacerbations
NSAIDs for symptom relief (no effect on disease progression)