Skin Lesions And Craniofacial Flashcards
Where Do melanocytes originate from?
Neural Crest cells
When is the risk of malignant transformation of a congenital melanocytic Nieves greatest in childhood?
Before age 9
What is the typical margin for atypical or dysplastic Nieves?
2 mm margins
What is a Nevus spilus ?
And irregularly shaped light brown spot with darkly, pigmented, macules, or papules distributed in the lesion
Puetz jeghers syndrome
AD; multiple lentigines and GI polyps
What is a halo Nevus
A melanocytic Nieves, surrounded by an area of depigmentation, usually found on the trunk of teenagers
Most common vascular neoplasm of childhood
Hemangioma
What is a port wine stain?
Capillary malformation that presents at birth and grows proportionate to gross and has normal endothelial cell turnover
How to treat a port wine stain
Pulsed dye laser of 585 wavelength and short duration
What is the inheritance pattern of a disease that presents with multiple glomus tumors?
Autosomal dominant
What syndrome has telangiectasia on the face lips, tongue, ears, hands feet G.I. GU pulmonary CNS and liver
Ozler Weber Renu syndrome, hereditary hemorrhagic. Telangiectasia
True or false pyogenic granulomas often develop as rapidly growing bleeding papules during pregnancy
True
What is PHACE syndrome?
Posterior fossa abnormalities, hemangiomas, arterial lesions, coarctation of the aorta, cardiac malformations, eye abnormalities
What is a solitary firm hyperkeratotic sometimes pedunculated papule frequently found on the digits overlying and IP joint, but can be found anywhere on the hands and feet
Acquired digital fibrokeratoma
What is a lesion that is skin colored or red found on the lateral or dorsal surface of a digit on an infant or young child
Infantile, digital fibromatosis
Most common side effects of using steroids for the treatment of keloids
Dermal atrophy and hypo pigmentation
Most common malignant tumor that can arise in a Nieves sebaceous
Basal cell carcinoma
Which reddish brown lesion exhibits Darier’s sign meaning urticates upon stroking
Cutaneous mastocytoma
What are treatment modalities for actinic keratosis?
Excision, curettage, 5FU, laser, ablation, dermabrasion, chemical, peels, cryosurgery
What is actinic cheilitis
Scaly fissure lesion in the lower lip, which is secondary to chronic ultraviolet light exposure. Squamous cell carcinoma can develop from this.
What are the high-risk HPV types?
16 and 18
Most common subcutaneous soft tissue tumors
Lipomas
What are angiolipomas
Painful subcutaneous nodules that are otherwise similar to lipomas
What are the cutaneous findings in Gardner syndrome?
Epidermal, inclusion cyst, osteomas, fibromas, lipomas, Leo myomas, Desmo, tumors, fibrosarcoma
APC mutation