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SBL > Skin Changes in Disease > Flashcards

Skin Changes in Disease Flashcards

1
Q

Rash seen in measles

A

brick red, irregular, maculopapular rash that appears 3-4 days after onset of prodrome; begins on the face and proceeds down and out

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2
Q

Measles prodrome

A

fever, cough, coryza, conjunctivitis

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3
Q

Pathognomic skin change of measles

A

koplik spots on buccal mucosa

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4
Q

Characteristic rash in erythema infectiosum

A

fiery red “slapped cheek” appearance, circumoral pallor, lacy rash on trunk

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5
Q

Parvovirus is one of the most common causes of what disease in childhood?

A

myocarditis

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6
Q

Parvo B19 sxs in women

A

can mimic SLE, RA, systemic sclerosis, vasculitis, etc.

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7
Q

Ehrlichiosis

A

rickettsial infection common in Missouri; sxs include fever, chills, HA, malaise, myalgia, N/V, anorexia, abdominal pain, calf pain, edema of dorsal hands

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8
Q

Characteristic rash of ehrlichiosis

A

erythematous macules or papules, petechiae, or diffuse erythema that begins approx 5 days after onset of systemic symptoms

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9
Q

Systemic manifestations of Ehrlichiosis

A

resp (cough, dyspnea, adult RDS), neuro (meningoencephalitis, AMS), renal failure, DIC, pericarditis

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10
Q

Characteristic rash of Lyme Disease

A

erythema migrans, flat or slightly raised red lesion that expands with central clearing

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11
Q

Stage 1 Lyme disease

A

flat or slightly raised red lesion at bite site about one week after bite; concomitant viral-like illness develops

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12
Q

Stage 2 Lyme disease

A

bacteremia, lesions similar to primary lesion but smaller; malaise, fatigue, fever, HA, neck pain, neuro manifestations

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13
Q

Stage 3 Lyme disease

A

MSK manifestations, monoarticular or oligoarticular, neuro manifestations, acrodermatitis chronicum atrophicans

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14
Q

Infectious mononucleosis sxs

A

malaise, fever, sore throat, palatal petechiae, LAD, splenomegaly, maculopopular rash

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15
Q

Complications of infections mono

A

hepatitis, myocarditis, neuropathy, encephalitis, airway obstruction, thrombocytopenia

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16
Q

Two major clinical stages of syphilis

A

early and late, separated by latency period

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17
Q

Early syphilis skin changes

A

chancre, secondary lesion involving skin and mucous membranes

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18
Q

Late syphilis skin changes

A

gummatous lesions involving skin, bones, viscera

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19
Q

Skin and mucous membrane changes in secondary syphilis

A

diffuse, macuar, papular, pustular, condyloma lata, painless/silvery ulcerations in mucous membrane

20
Q

Constitutional symptoms of secondary syphilis

A

low-grade fever, malaise, anorexia, arthralgias, myalgias

21
Q

Clinical findings Hand-foot-and-mouth disease

A

stomatitis, vesicular rash on hands and feet, nail dystrophies

22
Q

Clinical findings herpangina

A

sudden-onset fevers, HA, myalgias, petechiae or papules on soft palate that ulcerate and then heal

23
Q

Characteristic skin change of HFMD

A

vesicular eruption on palms and soles; bright pink macules that progress to vesicles with erythema; may form yellow to gray erosions

24
Q

Coxsackivirus complications

A

epidemic pleurodynia, aseptic meningitis, acute pericarditis

25
Q

Toxic Shock Syndrome clinical findings

A

abrupt fever, vomiting, watery diarrhea; diffuse macular erythematous rash and non-purulent conjunctivitis

26
Q

Scarlet fever caused by…

A

Grp A Strep pyogenes

27
Q

Most common cause of tonsillopharyngitis in children and adolescents

A

Streptococcus pyogenes

28
Q

Scarlet fever clinical findings

A

exudative pharyngitis, fever, scarlatiniform rash; strawberry tongue, exudative tonsillitis

29
Q

Scarlet fever prodrome

A

0.5 to 2 days of malaise, sore throat, fever, vomiting

30
Q

Scarlet fever characteristic rash

A

generalized, punctate, red, cirumoral pallor; fine desquamation involves hands and feet

31
Q

Erythema Multiforme

A

rare cutaneous eruption characterized by “target” lesions on face and extremities

32
Q

Infections that cause erythema multiforme

A

HSV, Mycoplasma pneumoniae (look for sxs of resp infx or influenza-like illness

33
Q

Characteristic rash of varicella

A

progression of rose-colored macules to papules, vesicles, pustules, and crusts; face, scalp, trunk, sparing extremities

34
Q

Gonococcemia infectious agent

A

N. gonorrhoeae, gram-negative, aerobic coccus-shaped bacterium found in pairs

35
Q

Classic triad of gonococcemia

A

dermatitis, migratory polyarthritis, tenosynovitis

36
Q

Skin findings of gonococcemia

A

small to medium macules or hemorrhagic vesicopustules on an erythematous base on palms and soles; may develop necrotic centers, “gun metal gray”

37
Q

Meningococcemia infectious agent

A

N. meningitidis

38
Q

Presentation of meningococcal infection

A

meningitis, acute meningococcemia, or chronic meningococcemia

39
Q

Rash in acute meningococcemia

A

petechial rash; rose-colored macules and papules

40
Q

TTP pentad

A

thrombocytopenia, microangiopathic hemolytic anemia, neuro sxs, fever, renal failure

41
Q

DDx palpable purpura

A

vasculitis (SLE, Sjogren’s, Henoch-Scholein, RA) and infection (endocarditis, gonococcemia, meningococcemia)

42
Q

DDx non-palpable purpura

A

ITP, TTP, DIC, clotting factor defect

43
Q

Most common form of cutaneous skin CA

A

Basal cell carcinoma

44
Q

characteristic appearance of basal cell carcinoma

A

pearly papule, erythematous patch; waxy, “pearly” appearance with telangiectasias

45
Q

characteristic appearance of squamous cell carcinoma

A

nonhealing ulcer; small red, conical, hard nodules

46
Q

Melanoma risk factors

A

sunburns, blue or green eyes, blonde or red hair, fair complexion, prior personal or family history

47
Q

Most common location of melanoma

A

back for men, lower extremities for women

SBL (21 decks)

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